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DTaP-IPV//PRP~T combined vaccine
DTaP-IPV//PRP~T combined vaccine is a Inactivated pentavalent vaccine Biologic drug developed by Sanofi. It is currently in Phase 3 development for Primary immunization against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b in infants and children. Also known as: PENTAXIM™.
This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b.
This combined vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b. Used for Primary immunization against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b in infants and children.
At a glance
| Generic name | DTaP-IPV//PRP~T combined vaccine |
|---|---|
| Also known as | PENTAXIM™ |
| Sponsor | Sanofi |
| Drug class | Inactivated pentavalent vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
DTaP-IPV//PRP~T is a pentavalent inactivated vaccine combining five separate immunizations into one injection. It contains inactivated toxoids of diphtheria and tetanus, acellular pertussis antigens, inactivated poliovirus types 1/2/3, and conjugated Haemophilus influenzae type b capsular polysaccharide. Upon administration, these antigens trigger both humoral (antibody) and cell-mediated immune responses, conferring protection against these five serious bacterial and viral pathogens.
Approved indications
- Primary immunization against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b in infants and children
Common side effects
- Injection site pain, erythema, or swelling
- Fever
- Irritability or fussiness
- Drowsiness
- Loss of appetite
- Vomiting
Key clinical trials
- Post-marketing Surveillance Study for the Safety of a DTaP-IPV- HB-PRP~T Vaccine in Republic of Korea
- Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (PHASE3)
- Immunogenicity and Safety of Diphtheria, Tetanus, Pertussis (DTaP) Vaccine in 3-month-old Infants (PHASE3)
- Safety of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers (PHASE3)
- Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the Russian Federation and Mexico (PHASE3)
- DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants (PHASE3)
- Immunogenicity and Safety of Sanofi Pasteur's Combined Vaccine Given as a Three-Dose Primary Series at 2, 3,4 Months of Age and Followed by a Booster Dose Given at 16 to 17 Months of Age in Vietnamese Infants Who Previously Received a Dose of Hepatitis B Vaccine at Birth or Within 1 Week After Birth (PHASE3)
- Concomitant Administration of a New Hexavalent Vaccine With a Meningococcal Serogroup C Conjugate Vaccine in Healthy Infants During Primary Series Immunisation Followed by Booster Vaccination (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- DTaP-IPV//PRP~T combined vaccine CI brief — competitive landscape report
- DTaP-IPV//PRP~T combined vaccine updates RSS · CI watch RSS
- Sanofi portfolio CI
Frequently asked questions about DTaP-IPV//PRP~T combined vaccine
What is DTaP-IPV//PRP~T combined vaccine?
How does DTaP-IPV//PRP~T combined vaccine work?
What is DTaP-IPV//PRP~T combined vaccine used for?
Who makes DTaP-IPV//PRP~T combined vaccine?
Is DTaP-IPV//PRP~T combined vaccine also known as anything else?
What drug class is DTaP-IPV//PRP~T combined vaccine in?
What development phase is DTaP-IPV//PRP~T combined vaccine in?
What are the side effects of DTaP-IPV//PRP~T combined vaccine?
Related
- Drug class: All Inactivated pentavalent vaccine drugs
- Manufacturer: Sanofi — full pipeline
- Therapeutic area: All drugs in Immunology / Infectious Disease
- Indication: Drugs for Primary immunization against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b in infants and children
- Also known as: PENTAXIM™
- Compare: DTaP-IPV//PRP~T combined vaccine vs similar drugs
- Pricing: DTaP-IPV//PRP~T combined vaccine cost, discount & access