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DTaP IPV//Hib vaccine
DTaP IPV//Hib vaccine is a vaccine Biologic drug developed by Sanofi Pasteur, a Sanofi Company. It is currently in Phase 3 development for Prevention of diphtheria in infants and children, Prevention of tetanus in infants and children, Prevention of pertussis (whooping cough) in infants and children. Also known as: Pentaxim™.
This combination vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b.
This combination vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b. Used for Prevention of diphtheria in infants and children, Prevention of tetanus in infants and children, Prevention of pertussis (whooping cough) in infants and children.
At a glance
| Generic name | DTaP IPV//Hib vaccine |
|---|---|
| Also known as | Pentaxim™ |
| Sponsor | Sanofi Pasteur, a Sanofi Company |
| Drug class | vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
DTaP IPV//Hib is a pentavalent vaccine containing inactivated toxoids (diphtheria and tetanus), acellular pertussis antigens, inactivated poliovirus, and Haemophilus influenzae type b conjugate. It works by presenting these antigens to the immune system, triggering both humoral (antibody) and cell-mediated immune responses that provide protection against these five infectious diseases.
Approved indications
- Prevention of diphtheria in infants and children
- Prevention of tetanus in infants and children
- Prevention of pertussis (whooping cough) in infants and children
- Prevention of poliomyelitis in infants and children
- Prevention of Haemophilus influenzae type b disease in infants and children
Common side effects
- Injection site erythema
- Injection site swelling
- Injection site pain
- Fever
- Irritability
- Drowsiness
Key clinical trials
- Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (PHASE3)
- Phase IV Clinical Study of sIPV Administration in Adolescent and Adult Populations (PHASE4)
- Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants (PHASE1, PHASE2)
- Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants (PHASE2)
- Adsorption of Cell-free Diphtheria and Tetanus (Three-component) Combined With Vaccine Phase III Clinical Trial (PHASE3)
- A Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed(DTcP) (PHASE3)
- Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine When Co-administered With Routine Pediatric Vaccines in Healthy Infants and Toddlers in Europe (PHASE3)
- The Effect of Mechanical Vibration and Helfer Skin Tap Technique on Procedural Pain in Infants During Vaccination (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- DTaP IPV//Hib vaccine CI brief — competitive landscape report
- DTaP IPV//Hib vaccine updates RSS · CI watch RSS
- Sanofi Pasteur, a Sanofi Company portfolio CI
Frequently asked questions about DTaP IPV//Hib vaccine
What is DTaP IPV//Hib vaccine?
How does DTaP IPV//Hib vaccine work?
What is DTaP IPV//Hib vaccine used for?
Who makes DTaP IPV//Hib vaccine?
Is DTaP IPV//Hib vaccine also known as anything else?
What drug class is DTaP IPV//Hib vaccine in?
What development phase is DTaP IPV//Hib vaccine in?
What are the side effects of DTaP IPV//Hib vaccine?
Related
- Drug class: All vaccine drugs
- Manufacturer: Sanofi Pasteur, a Sanofi Company — full pipeline
- Therapeutic area: All drugs in Immunology
- Indication: Drugs for Prevention of diphtheria in infants and children
- Indication: Drugs for Prevention of tetanus in infants and children
- Indication: Drugs for Prevention of pertussis (whooping cough) in infants and children
- Also known as: Pentaxim™
- Compare: DTaP IPV//Hib vaccine vs similar drugs
- Pricing: DTaP IPV//Hib vaccine cost, discount & access