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DTaP-IPV-Hib-HepB vaccine
DTaP-IPV-Hib-HepB vaccine is a vaccine Biologic drug developed by Sanofi Pasteur, a Sanofi Company. It is currently in Phase 3 development for Active immunization against diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b, and hepatitis B in infants and children. Also known as: Hexaxim®.
This combination vaccine stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b, and hepatitis B pathogens.
This combination vaccine stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b, and hepatitis B pathogens. Used for Active immunization against diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b, and hepatitis B in infants and children.
At a glance
| Generic name | DTaP-IPV-Hib-HepB vaccine |
|---|---|
| Also known as | Hexaxim® |
| Sponsor | Sanofi Pasteur, a Sanofi Company |
| Drug class | vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
DTaP-IPV-Hib-HepB is a hexavalent vaccine containing inactivated toxoids (diphtheria and tetanus), inactivated pertussis antigens, inactivated poliovirus, Haemophilus influenzae type b conjugate, and hepatitis B surface antigen. Upon administration, these antigens trigger both humoral and cellular immune responses, leading to the production of protective antibodies and memory cells against all six pathogens.
Approved indications
- Active immunization against diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b, and hepatitis B in infants and children
Common side effects
- Injection site reactions (pain, redness, swelling)
- Fever
- Irritability
- Drowsiness
- Loss of appetite
Key clinical trials
- Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (PHASE3)
- Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants (PHASE1, PHASE2)
- Study to Evaluate the Immunogenicity of LR20062 Compared to Control When Administered Intramuscularly in Healthy Infants At 2, 4, 6 Months of Age (PHASE2)
- A Study to Evaluate Safety and Immunogenicity of APV006 in Healthy Adults (PHASE1)
- Hepatitis B Vaccination in Infants (PHASE4)
- Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 4, and 11 to 12 Months (V419-008) (PHASE3)
- Concomitant Administration of a New Hexavalent Vaccine With a Meningococcal Serogroup C Conjugate Vaccine in Healthy Infants During Primary Series Immunisation Followed by Booster Vaccination (PHASE3)
- Study of the DTaP-IPV-Hep B-PRP~T Combined Vaccine Following a Primary Series of DTacP IPV-HepB-PRP-T or Infanrix Hexa™ (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- DTaP-IPV-Hib-HepB vaccine CI brief — competitive landscape report
- DTaP-IPV-Hib-HepB vaccine updates RSS · CI watch RSS
- Sanofi Pasteur, a Sanofi Company portfolio CI
Frequently asked questions about DTaP-IPV-Hib-HepB vaccine
What is DTaP-IPV-Hib-HepB vaccine?
How does DTaP-IPV-Hib-HepB vaccine work?
What is DTaP-IPV-Hib-HepB vaccine used for?
Who makes DTaP-IPV-Hib-HepB vaccine?
Is DTaP-IPV-Hib-HepB vaccine also known as anything else?
What drug class is DTaP-IPV-Hib-HepB vaccine in?
What development phase is DTaP-IPV-Hib-HepB vaccine in?
What are the side effects of DTaP-IPV-Hib-HepB vaccine?
Related
- Drug class: All vaccine drugs
- Manufacturer: Sanofi Pasteur, a Sanofi Company — full pipeline
- Therapeutic area: All drugs in Immunology
- Indication: Drugs for Active immunization against diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b, and hepatitis B in infants and children
- Also known as: Hexaxim®
- Compare: DTaP-IPV-Hib-HepB vaccine vs similar drugs
- Pricing: DTaP-IPV-Hib-HepB vaccine cost, discount & access