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DTaP-HB-PRP~T vaccine + OPV
DTaP-HB-PRP~T vaccine + OPV is a vaccine Biologic drug developed by Sanofi Pasteur, a Sanofi Company. It is currently in Phase 3 development for Primary immunization against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis in infants and children.
This combination vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliovirus.
This combination vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliovirus. Used for Primary immunization against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis in infants and children.
At a glance
| Generic name | DTaP-HB-PRP~T vaccine + OPV |
|---|---|
| Sponsor | Sanofi Pasteur, a Sanofi Company |
| Drug class | vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
DTaP-HB-PRP~T is a hexavalent vaccine containing inactivated toxoids (diphtheria, tetanus), acellular pertussis antigens, hepatitis B surface antigen, Haemophilus influenzae type b conjugate, combined with oral polio vaccine (OPV) containing live attenuated poliovirus strains. The vaccine triggers both humoral and cell-mediated immune responses to provide protection against these six infectious diseases.
Approved indications
- Primary immunization against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis in infants and children
Common side effects
- Injection site reactions (pain, redness, swelling)
- Fever
- Irritability or fussiness
- Drowsiness
- Loss of appetite
Key clinical trials
- Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (PHASE3)
- Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB PRP~T Combined Vaccine in Filipino Infants (PHASE3)
- Comparison of DTaP-IPV-Hep B-PRP~T Combined Vaccine to CombAct-HIB® Concomitantly Given With Engerix B® Paediatric and OPV (PHASE3)
- Safety of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared to Tritanrix-HepB/Hib™ and OPV Given at Age 2, 4, and 6 Months. (PHASE3)
- Comparison of DTaP-HB-PRP~T Combined Vaccine to Tritanrix-HepB/Hib™, Both Given Concomitantly With Oral Polio Vaccine (PHASE3)
- Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB-PRP~T Combined Vaccine or Tritanrix-HepB/Hib™ (PHASE3)
- Study Comparing a DTaP-HB-PRP~T Combined Vaccine With Tritanrix HepB/Hib™, Concomitantly With OPV in Healthy Infants (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- DTaP-HB-PRP~T vaccine + OPV CI brief — competitive landscape report
- DTaP-HB-PRP~T vaccine + OPV updates RSS · CI watch RSS
- Sanofi Pasteur, a Sanofi Company portfolio CI
Frequently asked questions about DTaP-HB-PRP~T vaccine + OPV
What is DTaP-HB-PRP~T vaccine + OPV?
How does DTaP-HB-PRP~T vaccine + OPV work?
What is DTaP-HB-PRP~T vaccine + OPV used for?
Who makes DTaP-HB-PRP~T vaccine + OPV?
What drug class is DTaP-HB-PRP~T vaccine + OPV in?
What development phase is DTaP-HB-PRP~T vaccine + OPV in?
What are the side effects of DTaP-HB-PRP~T vaccine + OPV?
Related
- Drug class: All vaccine drugs
- Manufacturer: Sanofi Pasteur, a Sanofi Company — full pipeline
- Therapeutic area: All drugs in Immunology
- Indication: Drugs for Primary immunization against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis in infants and children
- Compare: DTaP-HB-PRP~T vaccine + OPV vs similar drugs
- Pricing: DTaP-HB-PRP~T vaccine + OPV cost, discount & access