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Dropless Regimen
A perioperative anti-inflammatory regimen that eliminates the need for postoperative topical corticosteroid and nonsteroidal anti-inflammatory eye drops following cataract surgery.
A perioperative anti-inflammatory regimen that eliminates the need for postoperative topical corticosteroid and nonsteroidal anti-inflammatory eye drops following cataract surgery. Used for Postoperative inflammation and pain management following cataract surgery.
At a glance
| Generic name | Dropless Regimen |
|---|---|
| Sponsor | University of California, San Francisco |
| Drug class | Anti-inflammatory combination regimen |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
The dropless regimen uses sustained-release or long-acting anti-inflammatory agents (typically corticosteroids and NSAIDs) administered intraoperatively or perioperatively via intracameral injection, subconjunctival injection, or oral formulations to provide extended anti-inflammatory coverage without requiring patient-administered topical drops. This approach reduces inflammation, pain, and the risk of corneal complications while improving patient compliance by eliminating the need for multiple daily eye drop instillations.
Approved indications
- Postoperative inflammation and pain management following cataract surgery
Common side effects
- Corneal edema
- Elevated intraocular pressure
- Anterior chamber inflammation
Key clinical trials
- Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population (PHASE4)
- Dropless™ vs. Less Drops™ Pharmaceutical Regimens After Cataract Surgery (PHASE4)
- Dropless vs. Standard Drops Contralateral Eye Study (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Dropless Regimen CI brief — competitive landscape report
- Dropless Regimen updates RSS · CI watch RSS
- University of California, San Francisco portfolio CI