{"id":"dropless-regimen","safety":{"commonSideEffects":[{"rate":null,"effect":"Corneal edema"},{"rate":null,"effect":"Elevated intraocular pressure"},{"rate":null,"effect":"Anterior chamber inflammation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The dropless regimen uses sustained-release or long-acting anti-inflammatory agents (typically corticosteroids and NSAIDs) administered intraoperatively or perioperatively via intracameral injection, subconjunctival injection, or oral formulations to provide extended anti-inflammatory coverage without requiring patient-administered topical drops. This approach reduces inflammation, pain, and the risk of corneal complications while improving patient compliance by eliminating the need for multiple daily eye drop instillations.","oneSentence":"A perioperative anti-inflammatory regimen that eliminates the need for postoperative topical corticosteroid and nonsteroidal anti-inflammatory eye drops following cataract surgery.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:45:01.194Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Postoperative inflammation and pain management following cataract surgery"}]},"trialDetails":[{"nctId":"NCT05157113","phase":"PHASE4","title":"Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population","status":"RECRUITING","sponsor":"University of California, San Francisco","startDate":"2022-05-31","conditions":"Cataract, Surgery, Compliance, Patient","enrollment":70},{"nctId":"NCT02819908","phase":"PHASE4","title":"Dropless™ vs. Less Drops™ Pharmaceutical Regimens After Cataract Surgery","status":"COMPLETED","sponsor":"Eye Center of North Florida","startDate":"2015-09","conditions":"Intraocular Lens Associated Postoperative Inflammation","enrollment":25},{"nctId":"NCT02515045","phase":"PHASE4","title":"Dropless vs. Standard Drops Contralateral Eye Study","status":"COMPLETED","sponsor":"Carolina Eyecare Physicians, LLC","startDate":"2015-01","conditions":"Cataract","enrollment":59}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":13,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Dropless Regimen","genericName":"Dropless Regimen","companyName":"University of California, San Francisco","companyId":"university-of-california-san-francisco","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A perioperative anti-inflammatory regimen that eliminates the need for postoperative topical corticosteroid and nonsteroidal anti-inflammatory eye drops following cataract surgery. Used for Postoperative inflammation and pain management following cataract surgery.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}