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Doxil and Vinorelbine
Doxil and Vinorelbine is a Vinca alkaloid and microtubule inhibitor Small molecule drug developed by Hematology Oncology Consultants. It is currently in Phase 2 development for Breast cancer, Lung cancer.
Docetaxel, a microtubule inhibitor, binds to tubulin and prevents microtubule assembly, thereby inhibiting cell division.
Docetaxel, a microtubule inhibitor, binds to tubulin and prevents microtubule assembly, thereby inhibiting cell division. Used for Breast cancer, Lung cancer.
At a glance
| Generic name | Doxil and Vinorelbine |
|---|---|
| Sponsor | Hematology Oncology Consultants |
| Drug class | Vinca alkaloid and microtubule inhibitor |
| Target | Tubulin |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 2 |
Mechanism of action
This leads to cell cycle arrest at the G2/M phase and ultimately apoptosis. Vinorelbine, a vinca alkaloid, binds to tubulin and prevents microtubule polymerization, also inhibiting cell division.
Approved indications
- Breast cancer
- Lung cancer
Common side effects
- Neutropenia
- Anemia
- Thrombocytopenia
Key clinical trials
- CCCG-ALCL-2020 for Chinese Children and Adolescents With Newly Diagnosed High-risk ALCL (PHASE3)
- ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin Lymphoma (PHASE2)
- Tislelizumab Monotherapy Versus Salvage Chemotherapy for Relapsed/Refractory Classical Hodgkin Lymphoma (PHASE3)
- Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma (PHASE2)
- Evolutionary Therapy for Rhabdomyosarcoma (PHASE2)
- A Study of BV-AVD in People With Bulky Hodgkin Lymphoma (PHASE2)
- RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT) (PHASE2)
- Microdevice In Ovarian, Fallopian Tube, And Peritoneal Cancer (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Doxil and Vinorelbine CI brief — competitive landscape report
- Doxil and Vinorelbine updates RSS · CI watch RSS
- Hematology Oncology Consultants portfolio CI
Frequently asked questions about Doxil and Vinorelbine
What is Doxil and Vinorelbine?
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Related
- Drug class: All Vinca alkaloid and microtubule inhibitor drugs
- Target: All drugs targeting Tubulin
- Manufacturer: Hematology Oncology Consultants — full pipeline
- Therapeutic area: All drugs in Oncology
- Indication: Drugs for Breast cancer
- Indication: Drugs for Lung cancer
- Compare: Doxil and Vinorelbine vs similar drugs
- Pricing: Doxil and Vinorelbine cost, discount & access