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Dosage of Calcium edetate de sodium
Dosage of Calcium edetate de sodium is a Heavy metal chelating agent Small molecule drug developed by University Hospital, Limoges. It is currently in Phase 3 development for Lead poisoning (acute and chronic lead intoxication), Heavy metal toxicity.
Sodium calcium edetate is a chelating agent that binds and removes heavy metals (particularly lead) from the body by forming stable complexes that are excreted in urine.
Sodium calcium edetate is a chelating agent that binds and removes heavy metals (particularly lead) from the body by forming stable complexes that are excreted in urine. Used for Lead poisoning (acute and chronic lead intoxication), Heavy metal toxicity.
At a glance
| Generic name | Dosage of Calcium edetate de sodium |
|---|---|
| Sponsor | University Hospital, Limoges |
| Drug class | Heavy metal chelating agent |
| Target | Lead and other heavy metal ions (Pb²⁺, Cd²⁺, Zn²⁺) |
| Modality | Small molecule |
| Therapeutic area | Toxicology |
| Phase | Phase 3 |
Mechanism of action
Sodium calcium edetate contains a chelating ligand (ethylenediaminetetraacetic acid) that forms tight coordination complexes with divalent and trivalent metal ions, most notably lead. The drug preferentially exchanges its calcium for toxic metals in the bloodstream and tissues, allowing the metal-chelate complexes to be renally eliminated while minimizing depletion of essential minerals.
Approved indications
- Lead poisoning (acute and chronic lead intoxication)
- Heavy metal toxicity
Common side effects
- Nephrotoxicity / acute kidney injury
- Hypocalcemia
- Fever
- Myalgia / arthralgia
- Gastrointestinal disturbance
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Dosage of Calcium edetate de sodium CI brief — competitive landscape report
- Dosage of Calcium edetate de sodium updates RSS · CI watch RSS
- University Hospital, Limoges portfolio CI
Frequently asked questions about Dosage of Calcium edetate de sodium
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Related
- Drug class: All Heavy metal chelating agent drugs
- Target: All drugs targeting Lead and other heavy metal ions (Pb²⁺, Cd²⁺, Zn²⁺)
- Manufacturer: University Hospital, Limoges — full pipeline
- Therapeutic area: All drugs in Toxicology
- Indication: Drugs for Lead poisoning (acute and chronic lead intoxication)
- Indication: Drugs for Heavy metal toxicity
- Compare: Dosage of Calcium edetate de sodium vs similar drugs
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