Last reviewed 2026-04-23 · How we verify

Diprosone® ointment

Glucocorticoid receptor agonist

Glucocorticoid receptor agonist Used for Atopic dermatitis, Psoriasis, Seborrhoeic dermatitis.

At a glance

Mechanism of action

Diprosone ointment contains betamethasone valerate, a synthetic glucocorticoid that acts by binding to the glucocorticoid receptor, leading to anti-inflammatory and immunosuppressive effects.

Approved indications

• Atopic dermatitis
• Psoriasis
• Seborrhoeic dermatitis

Common side effects

• Skin atrophy
• Hypersensitivity reactions

Key clinical trials

• A Psoriasis Plaque Test With LEO 29102 Cream and Its Combination Products (PHASE2)
• LEO 90105 Ointment in Japanese Subjects With Psoriasis (PHASE3)
• Efficacy and Safety of LEO 90100 Foam in Japanese Subjects With Psoriasis Vulgaris (PHASE3)
• LEO 80185 Gel (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Japanese Subjects With Psoriasis (PHASE3)
• A Psoriasis Plaque Test Study With LEO 90100 Cutaneous Spray, Ointment, in Psoriasis Vulgaris (PHASE2)
• A Vasoconstriction Study With LEO 90100 (PHASE1)
• Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Ointment in Patients With Psoriasis Vulgaris (PHASE4)
• An Exploratory Psoriasis Plaque Test Study With LEO 29102 Plus Calcipotriol, Ointment, in Psoriasis Vulgaris (PHASE1)

Primary sources

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Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• Diprosone® ointment CI brief — competitive landscape report
• Diprosone® ointment updates RSS · CI watch RSS
• LEO Pharma portfolio CI