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Dexketoprofen/Vitamin B
Dexketoprofen inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis and inflammation, while vitamin B provides nutritional support and may enhance analgesic efficacy.
Dexketoprofen inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis and inflammation, while vitamin B provides nutritional support and may enhance analgesic efficacy. Used for Acute and chronic pain conditions, Inflammatory conditions (arthritis, musculoskeletal pain).
At a glance
| Generic name | Dexketoprofen/Vitamin B |
|---|---|
| Also known as | D/VitB |
| Sponsor | Laboratorios Silanes S.A. de C.V. |
| Drug class | NSAID with vitamin supplement |
| Target | COX-1, COX-2 |
| Modality | Small molecule |
| Therapeutic area | Pain Management / Rheumatology |
| Phase | Phase 3 |
Mechanism of action
Dexketoprofen is the active S-enantiomer of ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) that blocks COX-1 and COX-2 enzymes, thereby reducing pain, inflammation, and fever. The addition of vitamin B (likely B-complex vitamins) may support nerve function and potentially enhance the analgesic effect through nutritional supplementation, making this a combination product targeting pain management.
Approved indications
- Acute and chronic pain conditions
- Inflammatory conditions (arthritis, musculoskeletal pain)
Common side effects
- Gastrointestinal upset (nausea, dyspepsia)
- Abdominal pain
- Headache
- Dizziness
- Gastric ulceration (with chronic use)
Key clinical trials
- Efficacy and Safety of Dexketoprofen/Vitamin B Vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II (PHASE3)
- Comparison of Bioavailability of Dexketoprofen-Vit B vs Dexketoprofen, in Healthy Subjects, Under Fasting Conditions (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Dexketoprofen/Vitamin B CI brief — competitive landscape report
- Dexketoprofen/Vitamin B updates RSS · CI watch RSS
- Laboratorios Silanes S.A. de C.V. portfolio CI