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Deep-frozen platelets
Deep-frozen platelets are cryopreserved blood platelets that are thawed and transfused to restore hemostatic function in patients with thrombocytopenia or platelet dysfunction.
Deep-frozen platelets are cryopreserved blood platelets that are thawed and transfused to restore hemostatic function in patients with thrombocytopenia or platelet dysfunction. Used for Thrombocytopenia requiring platelet transfusion support, Platelet refractoriness in hematologic and oncologic patients.
At a glance
| Generic name | Deep-frozen platelets |
|---|---|
| Also known as | Cryopreserved platelets |
| Sponsor | Alrijne Ziekenhuis Leiderdorp |
| Drug class | Blood product / Cellular therapy |
| Modality | Small molecule |
| Therapeutic area | Hematology / Transfusion Medicine |
| Phase | Phase 3 |
Mechanism of action
Platelets are isolated from donor blood, treated with cryoprotectants (typically DMSO), and frozen at ultra-low temperatures to preserve viability. Upon thawing and transfusion, these platelets restore platelet count and function to prevent or treat bleeding complications. This approach extends platelet shelf-life beyond the standard 5-day room-temperature storage, enabling better inventory management and availability.
Approved indications
- Thrombocytopenia requiring platelet transfusion support
- Platelet refractoriness in hematologic and oncologic patients
Common side effects
- Transfusion reaction (febrile, allergic)
- Alloimmunization
- Transfusion-related acute lung injury (TRALI)
- Bacterial contamination / sepsis
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Deep-frozen platelets CI brief — competitive landscape report
- Deep-frozen platelets updates RSS · CI watch RSS
- Alrijne Ziekenhuis Leiderdorp portfolio CI