Last reviewed · How we verify
CYD Dengue Vaccine Serotypes 1, 2, 3, and 4
CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 is a vaccine Biologic drug developed by Sanofi Pasteur, a Sanofi Company. It is currently in Phase 2 development for Prevention of dengue fever caused by dengue virus serotypes 1, 2, 3, and 4. Also known as: ChimeriVax™.
The CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 is a tetravalent dengue vaccine that targets the envelope proteins of all four dengue virus serotypes to induce a protective immune response.
The CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 is a tetravalent dengue vaccine that targets the envelope proteins of all four dengue virus serotypes to induce a protective immune response. Used for Prevention of dengue fever caused by dengue virus serotypes 1, 2, 3, and 4.
At a glance
| Generic name | CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 |
|---|---|
| Also known as | ChimeriVax™ |
| Sponsor | Sanofi Pasteur, a Sanofi Company |
| Drug class | vaccine |
| Target | Dengue virus envelope proteins (E proteins) |
| Modality | Biologic |
| Therapeutic area | Infectious Disease |
| Phase | Phase 2 |
Mechanism of action
This vaccine works by presenting the immune system with antigens from all four dengue serotypes, stimulating the production of neutralizing antibodies and memory B cells, which can provide protection against future infections by any of the serotypes.
Approved indications
- Prevention of dengue fever caused by dengue virus serotypes 1, 2, 3, and 4
Common side effects
- Injection site pain
- Headache
- Fatigue
Key clinical trials
- Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Subjects (PHASE2)
- Study of a Tetravalent Dengue Vaccine in Healthy Adult Subjects Aged 18 to 45 Years in India (PHASE2)
- Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Peruvian Children Aged 2 to 11 Years (PHASE2)
- Study of Yellow Fever Vaccine Administered With Tetravalent Dengue Vaccine in Healthy Toddlers (PHASE3)
- Study of a Booster Injection of Pentaxim™ Vaccine Administered With Dengue Vaccine in Healthy Toddlers (PHASE3)
- Study of a Tetravalent Dengue Vaccine in Healthy Children Aged 2 to 11 Years in Malaysia (PHASE3)
- Immune Response to Different Schedules of a Tetravalent Dengue Vaccine Given With or Without Yellow Fever Vaccine (PHASE2)
- Study of CYD Dengue Vaccine in Healthy Children and Adolescents in South America (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 CI brief — competitive landscape report
- CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 updates RSS · CI watch RSS
- Sanofi Pasteur, a Sanofi Company portfolio CI
Frequently asked questions about CYD Dengue Vaccine Serotypes 1, 2, 3, and 4
What is CYD Dengue Vaccine Serotypes 1, 2, 3, and 4?
How does CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 work?
What is CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 used for?
Who makes CYD Dengue Vaccine Serotypes 1, 2, 3, and 4?
Is CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 also known as anything else?
What drug class is CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 in?
What development phase is CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 in?
What are the side effects of CYD Dengue Vaccine Serotypes 1, 2, 3, and 4?
What does CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 target?
Related
- Drug class: All vaccine drugs
- Target: All drugs targeting Dengue virus envelope proteins (E proteins)
- Manufacturer: Sanofi Pasteur, a Sanofi Company — full pipeline
- Therapeutic area: All drugs in Infectious Disease
- Indication: Drugs for Prevention of dengue fever caused by dengue virus serotypes 1, 2, 3, and 4
- Also known as: ChimeriVax™
- Compare: CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 vs similar drugs
- Pricing: CYD Dengue Vaccine Serotypes 1, 2, 3, and 4 cost, discount & access