Creon IR is developed by Abbott.

What are the side effects of Creon IR?

Common side effects include Nausea, Diarrhea, Abdominal pain.

Last reviewed 2026-04-23 · How we verify

Creon IR

Abbott · Phase 2 active Small molecule

Pancreatic enzyme replacement

Pancreatic enzyme replacement Used for Treatment of exocrine pancreatic insufficiency due to cystic fibrosis or other conditions.

At a glance

Generic name	Creon IR
Sponsor	Abbott
Drug class	Pancreatic enzyme replacement
Modality	Small molecule
Therapeutic area	Gastroenterology
Phase	Phase 2

Mechanism of action

Creon IR is a pancreatic enzyme replacement that contains a mixture of lipase, amylase, and protease enzymes to help digest food in people with pancreatic insufficiency.

Approved indications

Treatment of exocrine pancreatic insufficiency due to cystic fibrosis or other conditions

Common side effects

Nausea
Diarrhea
Abdominal pain

Key clinical trials

Efficacy and Safety Study of Creon IR in Subjects With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis (PHASE2)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results