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corticosteroids'therapy
Corticosteroids suppress the immune system by inhibiting the production of inflammatory cytokines.
Corticosteroids suppress the immune system by inhibiting the production of inflammatory cytokines. Used for Rheumatoid arthritis, Asthma, Multiple sclerosis.
At a glance
| Generic name | corticosteroids'therapy |
|---|---|
| Sponsor | University Hospital, Rouen |
| Drug class | Corticosteroid |
| Modality | Small molecule |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
This is achieved through the binding of corticosteroids to glucocorticoid receptors, which then translocate to the nucleus and regulate the expression of genes involved in inflammation. As a result, corticosteroids reduce the production of pro-inflammatory cytokines and increase the production of anti-inflammatory cytokines, leading to a decrease in inflammation and immune response.
Approved indications
- Rheumatoid arthritis
- Asthma
- Multiple sclerosis
Common side effects
- Gastrointestinal bleeding
- Osteoporosis
- Glaucoma
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- corticosteroids'therapy CI brief — competitive landscape report
- corticosteroids'therapy updates RSS · CI watch RSS
- University Hospital, Rouen portfolio CI