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Coristina d
Coristina D is a combination antihistamine and decongestant that reduces allergy and cold symptoms by blocking histamine receptors and constricting nasal blood vessels.
Coristina D is a combination antihistamine and decongestant that reduces allergy and cold symptoms by blocking histamine receptors and constricting nasal blood vessels. Used for Symptomatic relief of allergic rhinitis, Symptomatic relief of common cold and upper respiratory congestion.
At a glance
| Generic name | Coristina d |
|---|---|
| Sponsor | Brainfarma Industria Química e Farmacêutica S/A |
| Drug class | Antihistamine/Decongestant combination |
| Target | H1 histamine receptor; alpha-1 adrenergic receptor |
| Modality | Small molecule |
| Therapeutic area | Allergy/Cold and Flu |
| Phase | Phase 3 |
Mechanism of action
The drug combines an antihistamine (likely chlorpheniramine or similar) to block H1 histamine receptors and reduce allergic symptoms such as itching and sneezing, with a decongestant (likely phenylephrine or pseudoephedrine) that acts as a sympathomimetic to constrict blood vessels in the nasal mucosa and reduce congestion. This dual mechanism provides symptomatic relief of both allergic and cold-related upper respiratory symptoms.
Approved indications
- Symptomatic relief of allergic rhinitis
- Symptomatic relief of common cold and upper respiratory congestion
Common side effects
- Drowsiness
- Dry mouth
- Nervousness or insomnia
- Headache
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Coristina d CI brief — competitive landscape report
- Coristina d updates RSS · CI watch RSS
- Brainfarma Industria Química e Farmacêutica S/A portfolio CI