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Combination - Tranilast and Febuxostat
Combination - Tranilast and Febuxostat is a Antiproliferative agent, Xanthine oxidase inhibitor Small molecule drug developed by Nuon Therapeutics, Inc.. It is currently in Phase 2 development for Gout, Malignant hypertension.
Tranilast is a selective inhibitor of PDGF receptors, while Febuxostat is a xanthine oxidase inhibitor.
Tranilast is a selective inhibitor of PDGF receptors, while Febuxostat is a xanthine oxidase inhibitor. Used for Gout, Malignant hypertension.
At a glance
| Generic name | Combination - Tranilast and Febuxostat |
|---|---|
| Sponsor | Nuon Therapeutics, Inc. |
| Drug class | Antiproliferative agent, Xanthine oxidase inhibitor |
| Target | PDGF receptor, Xanthine oxidase |
| Modality | Small molecule |
| Therapeutic area | Oncology, Cardiovascular |
| Phase | Phase 2 |
Mechanism of action
Tranilast works by blocking the PDGF receptors, which are involved in the proliferation and migration of smooth muscle cells. Febuxostat, on the other hand, inhibits xanthine oxidase, an enzyme involved in the production of uric acid.
Approved indications
- Gout, Malignant hypertension
Common side effects
- Diarrhea
- Nausea
- Headache
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Combination - Tranilast and Febuxostat CI brief — competitive landscape report
- Combination - Tranilast and Febuxostat updates RSS · CI watch RSS
- Nuon Therapeutics, Inc. portfolio CI
Frequently asked questions about Combination - Tranilast and Febuxostat
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Related
- Drug class: All Antiproliferative agent, Xanthine oxidase inhibitor drugs
- Target: All drugs targeting PDGF receptor, Xanthine oxidase
- Manufacturer: Nuon Therapeutics, Inc. — full pipeline
- Therapeutic area: All drugs in Oncology, Cardiovascular
- Indication: Drugs for Gout, Malignant hypertension
- Compare: Combination - Tranilast and Febuxostat vs similar drugs
- Pricing: Combination - Tranilast and Febuxostat cost, discount & access