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Collagen-PVP
Collagen-PVP is a Biomaterial/Wound healing agent Small molecule drug developed by Coordinación de Investigación en Salud, Mexico. It is currently in Phase 3 development for Wound healing and tissue regeneration. Also known as: Fibroquel.
Collagen-PVP is a composite biomaterial that combines collagen with polyvinylpyrrolidone to provide structural support and promote tissue regeneration and wound healing.
Collagen-PVP is a solution used in clinical trials for various conditions, including diabetes complications, perineal tear, and COVID-19, as well as a treatment for stenosing tenosynovitis in older adults with type 2 diabetes. It is an enzyme modality that targets a specific protease, likely related to its action on gliadin, based on its synonyms listed in ChEMBL.
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Baseline phase 3 → approval rate
+58.3pp
Industry-wide phase 3 drugs reach approval ~58.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
| Regulator | Country | Likely year | Lag vs FDA |
|---|---|---|---|
| FDA | US | 2028–2030 | — |
| EMA | EU | 2029–2031 | +0.7 yr |
| MHRA | GB | 2029–2031 | +0.7 yr |
| Health Canada | CA | 2029–2032 | +0.9 yr |
| TGA | AU | 2029–2032 | +1.2 yr |
| PMDA | JP | 2029–2032 | +1.5 yr |
| NMPA | CN | 2030–2033 | +2.3 yr |
| MFDS | KR | 2029–2032 | +1.4 yr |
| CDSCO | IN | 2029–2033 | +1.8 yr |
| ANVISA | BR | 2030–2033 | +2.3 yr |
Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).
Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.
At a glance
| Generic name | Collagen-PVP |
|---|---|
| Also known as | Fibroquel |
| Sponsor | Coordinación de Investigación en Salud, Mexico |
| Drug class | Biomaterial/Wound healing agent |
| Modality | Small molecule |
| Therapeutic area | Wound Care/Tissue Regeneration |
| Phase | Phase 3 |
Mechanism of action
The collagen component serves as a natural extracellular matrix scaffold that facilitates cell adhesion and tissue formation, while the PVP (polyvinylpyrrolidone) acts as a biocompatible polymer that enhances the material's physical properties, stability, and bioavailability. This combination is designed to support hemostasis, wound closure, and tissue repair through both structural and biological mechanisms.
Approved indications
- Wound healing and tissue regeneration
Common side effects
Key clinical trials
- Effect of Subcutaneous Polyvidone Collagen Treatment on Hand Recovery in Adult Rheumatoid Arthritis. (PHASE1, PHASE2)
- Pirfenidone LP or Collagen-polyvinylpyrrolidone in COVID-19 (PHASE2, PHASE3)
- Collagen-povidone for Diabetic Seniors' Tenosynovitis (PHASE4)
- Intraarticular Collagen in Patients With Gonarthrosis (NA)
- Lidocaine, Povidone Iodine, and Honey Application on Second-degree Perineal Tear Healing (PHASE4)
- Intramuscular Effect of Polymerized Type I Collagen on the Cytokine Storm in COVID-19 Patients (PHASE1, PHASE2)
- Collagen-PVP vs Hylan G-F 20 in the Treatment of Knee Osteoarthritis (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Collagen-PVP CI brief — competitive landscape report
- Collagen-PVP updates RSS · CI watch RSS
- Coordinación de Investigación en Salud, Mexico portfolio CI
Frequently asked questions about Collagen-PVP
What is Collagen-PVP?
How does Collagen-PVP work?
What is Collagen-PVP used for?
Who makes Collagen-PVP?
Is Collagen-PVP also known as anything else?
What drug class is Collagen-PVP in?
What development phase is Collagen-PVP in?
Related
- Drug class: All Biomaterial/Wound healing agent drugs
- Manufacturer: Coordinación de Investigación en Salud, Mexico — full pipeline
- Therapeutic area: All drugs in Wound Care/Tissue Regeneration
- Indication: Drugs for Wound healing and tissue regeneration
- Also known as: Fibroquel
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing