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COLD BLOOD BASED CARDIOPLEGIA
Cold blood-based cardioplegia is a solution used during cardiac surgery to induce cardiac arrest and protect the heart from ischemic injury by rapidly cooling and chemically arresting myocardial function.
Cold blood-based cardioplegia is a solution used during cardiac surgery to induce cardiac arrest and protect the heart from ischemic injury by rapidly cooling and chemically arresting myocardial function. Used for Myocardial protection during cardiac surgery requiring cardiopulmonary bypass.
At a glance
| Generic name | COLD BLOOD BASED CARDIOPLEGIA |
|---|---|
| Also known as | CARDIBRAUN |
| Sponsor | JESSICA GARCIA SUAREZ |
| Drug class | Cardioplegic solution |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
This cardioplegic solution combines cold temperature with electrolyte composition (typically high potassium) to stop the heart's electrical and mechanical activity, reducing myocardial oxygen demand during surgical procedures. The hypothermia provides metabolic protection to cardiac tissue, while the chemical composition maintains electrolyte balance and prevents reperfusion injury when normal circulation is restored.
Approved indications
- Myocardial protection during cardiac surgery requiring cardiopulmonary bypass
Common side effects
- Myocardial stunning
- Reperfusion injury
- Arrhythmias post-operatively
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- COLD BLOOD BASED CARDIOPLEGIA CI brief — competitive landscape report
- COLD BLOOD BASED CARDIOPLEGIA updates RSS · CI watch RSS
- JESSICA GARCIA SUAREZ portfolio CI