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Entumine (clotiapine)
Entumine (generic name: clotiapine) is a clotiapine drug. It is currently in unknown development.
Entumine works by blocking the D(2) dopamine receptor, which can help regulate abnormal dopamine activity in the brain.
Entumine (clotiapine) is a small molecule drug that targets the D(2) dopamine receptor. It is classified as a clotiapine, but its commercial status and approved indications are unknown. Entumine is not FDA-approved, and its half-life, bioavailability, and generic manufacturers are also unknown. As a result, its availability and safety profile are unclear. Further research is needed to determine its potential therapeutic applications and risks.
At a glance
| Generic name | clotiapine |
|---|---|
| Drug class | clotiapine |
| Target | D(2) dopamine receptor, D(1A) dopamine receptor, D(2) dopamine receptor |
| Therapeutic area | Neuroscience |
| Phase | unknown |
Mechanism of action
Think of dopamine like a messenger in your brain that helps you feel pleasure and motivation. When there's too much dopamine, it can lead to problems like psychosis or schizophrenia. Entumine helps by blocking the receptors that dopamine binds to, which can help calm down the abnormal activity and reduce symptoms.
Approved indications
Common side effects
- Sopor
- Drug abuse
- Toxicity to various agents
- Intentional self-injury
- Sudden death
- Depressed level of consciousness
- Suicide attempt
- Coma
Key clinical trials
- Clinical Trial to Evaluate the Efficacy of Treatment vs Discontinuation in a First Episode of Non-affective Psychosis (PHASE3)
- Investigation of the Safety, Tolerability and Potential Therapeutic Effects of JNJ-40411813 in Patients With Schizophrenia (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Entumine CI brief — competitive landscape report
- Entumine updates RSS · CI watch RSS
- portfolio CI
Frequently asked questions about Entumine
What is Entumine?
How does Entumine work?
What is the generic name of Entumine?
What drug class is Entumine in?
What development phase is Entumine in?
What are the side effects of Entumine?
What does Entumine target?
Related
- Drug class: All clotiapine drugs
- Target: All drugs targeting D(2) dopamine receptor, D(1A) dopamine receptor, D(2) dopamine receptor
- Manufacturer: — full pipeline
- Therapeutic area: All drugs in Neuroscience
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing