Last reviewed 2026-06-03 · How we verify

Chlorindion (CLORINDIONE)

Phase 2 active Small molecule ✓ Verified Jun 2026

Chlorindion (generic name: CLORINDIONE) is a clorindione drug. It is currently in Phase 2 development.

Chlorindione works by blocking a specific enzyme that helps blood clotting.

Chlorindion is a small molecule compound. It is also known by synonyms such as 2-(P-CHLOROPHENYL)-1,3-INDANDION, CLORINDIONA, CLORINDIONE, CLORINDIONE, G-25766, and NSC-758878.

Likelihood of approval

15.3% vs 15.3% industry baseline

If approved by FDA: likely 2031–2034

Steps remaining: Phase 3 → NDA/BLA submission

Confidence: Medium

Why this estimate

Baseline phase 2 → approval rate +15.3pp
Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).

Predicted approval windows by jurisdiction (conditional on FDA approval)

Regulator	Country	Likely year	Lag vs FDA
FDA	US	2031–2034	—
EMA	EU	2032–2035	+0.7 yr
MHRA	GB	2032–2035	+0.7 yr
Health Canada	CA	2032–2036	+0.9 yr
TGA	AU	2032–2036	+1.2 yr
PMDA	JP	2032–2036	+1.5 yr
NMPA	CN	2033–2037	+2.3 yr
MFDS	KR	2032–2036	+1.4 yr
CDSCO	IN	2032–2037	+1.8 yr
ANVISA	BR	2033–2037	+2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic name	CLORINDIONE
Drug class	clorindione
Target	Arachidonate 5-lipoxygenase
Modality	Small molecule
Therapeutic area	Hematology
Phase	Phase 2

Mechanism of action

Imagine your blood as a liquid that needs to turn into a solid to stop bleeding when you get hurt. Chlorindione helps this process by blocking an enzyme that's necessary for blood to clot. This can help people with bleeding disorders, but it also means they may be at risk of excessive bleeding if they take too much or have other health problems.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Chlorindion CI brief — competitive landscape report
Chlorindion updates RSS · CI watch RSS

Frequently asked questions about Chlorindion

What is Chlorindion?

Chlorindion (CLORINDIONE) is a clorindione drug.

How does Chlorindion work?

Chlorindione works by blocking a specific enzyme that helps blood clotting.

What is the generic name of Chlorindion?

CLORINDIONE is the generic (nonproprietary) name of Chlorindion.

What drug class is Chlorindion in?

Chlorindion belongs to the clorindione class. See all clorindione drugs at /class/clorindione.

What development phase is Chlorindion in?

Chlorindion is in Phase 2.

What does Chlorindion target?

Chlorindion targets Arachidonate 5-lipoxygenase and is a clorindione.

Drug class: All clorindione drugs
Target: All drugs targeting Arachidonate 5-lipoxygenase
Therapeutic area: All drugs in Hematology

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing