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Ciprofloxacin HCl and Hydrocortisone
Ciprofloxacin HCl and Hydrocortisone is a Fluoroquinolone antibiotic + corticosteroid combination Small molecule drug developed by Farmoquimica S.A.. It is currently in Phase 3 development for Acute otitis externa (swimmer's ear), Otitis media with effusion or tympanostomy tubes. Also known as: Otociriax.
Ciprofloxacin kills bacteria by inhibiting DNA gyrase and topoisomerase IV, while hydrocortisone reduces inflammation and immune response in the ear.
Ciprofloxacin kills bacteria by inhibiting DNA gyrase and topoisomerase IV, while hydrocortisone reduces inflammation and immune response in the ear. Used for Acute otitis externa (swimmer's ear), Otitis media with effusion or tympanostomy tubes.
At a glance
| Generic name | Ciprofloxacin HCl and Hydrocortisone |
|---|---|
| Also known as | Otociriax |
| Sponsor | Farmoquimica S.A. |
| Drug class | Fluoroquinolone antibiotic + corticosteroid combination |
| Target | Bacterial DNA gyrase and topoisomerase IV; glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Otology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
This is a fixed-dose combination designed for otic (ear) use. Ciprofloxacin is a fluoroquinolone antibiotic that prevents bacterial DNA replication by inhibiting essential enzymes. Hydrocortisone is a corticosteroid that suppresses local inflammation and immune-mediated tissue damage, reducing pain and swelling associated with ear infections.
Approved indications
- Acute otitis externa (swimmer's ear)
- Otitis media with effusion or tympanostomy tubes
Common side effects
- Ear irritation or discomfort
- Pruritus
- Headache
- Taste perversion
Key clinical trials
- Skin Toxicity Treatment in Metastatic Colorectal Cancer (mCRC) Patients Receiving Panitumumab + Irinotecan-based Therapy (PHASE2)
- A Comparative Study Between Two Formulations of the Ciprofloxacin Hydrochloride + Hydrocortisone Otic Suspension (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Ciprofloxacin HCl and Hydrocortisone CI brief — competitive landscape report
- Ciprofloxacin HCl and Hydrocortisone updates RSS · CI watch RSS
- Farmoquimica S.A. portfolio CI
Frequently asked questions about Ciprofloxacin HCl and Hydrocortisone
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Related
- Drug class: All Fluoroquinolone antibiotic + corticosteroid combination drugs
- Target: All drugs targeting Bacterial DNA gyrase and topoisomerase IV; glucocorticoid receptor
- Manufacturer: Farmoquimica S.A. — full pipeline
- Therapeutic area: All drugs in Otology / Infectious Disease
- Indication: Drugs for Acute otitis externa (swimmer's ear)
- Indication: Drugs for Otitis media with effusion or tympanostomy tubes
- Also known as: Otociriax
- Compare: Ciprofloxacin HCl and Hydrocortisone vs similar drugs
- Pricing: Ciprofloxacin HCl and Hydrocortisone cost, discount & access