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Chlorogenic acid for Injection
Chlorogenic acid acts as an antioxidant and anti-inflammatory agent by scavenging free radicals and inhibiting inflammatory pathways.
Chlorogenic acid acts as an antioxidant and anti-inflammatory agent by scavenging free radicals and inhibiting inflammatory pathways. Used for Liver injury and hepatoprotection (investigational), Renal protection and kidney disease (investigational).
At a glance
| Generic name | Chlorogenic acid for Injection |
|---|---|
| Also known as | CHA |
| Sponsor | Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd |
| Drug class | Antioxidant polyphenol |
| Modality | Small molecule |
| Therapeutic area | Hepatology; Nephrology; General antioxidant therapy |
| Phase | Phase 2 |
Mechanism of action
Chlorogenic acid is a polyphenolic compound that exerts cytoprotective effects through multiple mechanisms including free radical scavenging, inhibition of pro-inflammatory cytokine production, and modulation of oxidative stress. It has been investigated for its potential to reduce tissue damage and improve organ function in conditions characterized by oxidative stress and inflammation.
Approved indications
- Liver injury and hepatoprotection (investigational)
- Renal protection and kidney disease (investigational)
Common side effects
- Gastrointestinal disturbance
- Allergic reaction
Key clinical trials
- Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Grade IV GBM Patients (PHASE2, PHASE3)
- Phase Ib/IIa Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Advanced Lung Cancer (PHASE1, PHASE2)
- Phase I Studies of Chlorogenic Acid for Injection for Tolerance and Pharmacokinetic of Advanced Cancers (PHASE1)
- Tolerance and Pharmacokinetic Study of Chlorogenic Acid to Advanced Glioblastoma (PHASE1)
- Phase 1 Trial of Chlorogenic Acid in Patients With Advanced Cancer (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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