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CHG/IPA Surgical skin preparation
CHG/IPA Surgical skin preparation is a Surgical skin antiseptic / Antimicrobial preparation Small molecule drug developed by Solventum US LLC. It is currently in Phase 3 development for Surgical skin preparation and antisepsis prior to surgery. Also known as: 2% CHG/70% IPA.
CHG/IPA is a surgical skin antiseptic that combines chlorhexidine gluconate (CHG) and isopropyl alcohol (IPA) to rapidly kill bacteria and reduce surgical site infections.
CHG/IPA is a surgical skin antiseptic that combines chlorhexidine gluconate (CHG) and isopropyl alcohol (IPA) to rapidly kill bacteria and reduce surgical site infections. Used for Surgical skin preparation and antisepsis prior to surgery.
At a glance
| Generic name | CHG/IPA Surgical skin preparation |
|---|---|
| Also known as | 2% CHG/70% IPA |
| Sponsor | Solventum US LLC |
| Drug class | Surgical skin antiseptic / Antimicrobial preparation |
| Modality | Small molecule |
| Therapeutic area | Infection Prevention / Surgical |
| Phase | Phase 3 |
Mechanism of action
Chlorhexidine gluconate is a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, while isopropyl alcohol provides rapid antimicrobial activity and promotes quick drying. Together, they create a synergistic effect that reduces the microbial load on skin before surgical procedures, thereby lowering the risk of surgical site infections.
Approved indications
- Surgical skin preparation and antisepsis prior to surgery
Common side effects
- Skin irritation or erythema
- Contact dermatitis
- Allergic reaction
Key clinical trials
- A Pilot Study to Evaluate Skin Swabbing With Chlorhexidine to Prevent Skin And Soft Tissue Infections Among People Who Inject Drugs (PHASE4)
- In-vivo Efficacy Study of Patient Preoperative Preps (PHASE3)
- In-vivo Efficacy Study of Patient Pre-operative Preps (PHASE3)
- In Vivo Patient Preoperative Skin Prep Persistence (PHASE2)
- In Vivo Preoperative Skin Preparation Efficacy Study Within a Defined Product Coverage Area (PHASE2)
- Efficacy Study of Patient Preoperative Preps In-vivo (PHASE3)
- In Vivo Efficacy Study of Patient Preoperative Preps (PHASE3)
- Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- CHG/IPA Surgical skin preparation CI brief — competitive landscape report
- CHG/IPA Surgical skin preparation updates RSS · CI watch RSS
- Solventum US LLC portfolio CI
Frequently asked questions about CHG/IPA Surgical skin preparation
What is CHG/IPA Surgical skin preparation?
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What is CHG/IPA Surgical skin preparation used for?
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Is CHG/IPA Surgical skin preparation also known as anything else?
What drug class is CHG/IPA Surgical skin preparation in?
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Related
- Drug class: All Surgical skin antiseptic / Antimicrobial preparation drugs
- Manufacturer: Solventum US LLC — full pipeline
- Therapeutic area: All drugs in Infection Prevention / Surgical
- Indication: Drugs for Surgical skin preparation and antisepsis prior to surgery
- Also known as: 2% CHG/70% IPA
- Compare: CHG/IPA Surgical skin preparation vs similar drugs
- Pricing: CHG/IPA Surgical skin preparation cost, discount & access