Last reviewed · How we verify
CHG antiseptic body cleanser
CHG (chlorhexidine gluconate) is an antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, providing broad-spectrum antiseptic activity.
CHG (chlorhexidine gluconate) is an antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, providing broad-spectrum antiseptic activity. Used for Antiseptic skin cleansing and preoperative skin preparation, Prevention of skin and wound infections.
At a glance
| Generic name | CHG antiseptic body cleanser |
|---|---|
| Also known as | Chlorhexidine gluconate cloths, Drug Identification Number (Health Canada): 02245741 |
| Sponsor | Baycrest |
| Drug class | Antimicrobial antiseptic |
| Target | Bacterial cell membrane |
| Modality | Small molecule |
| Therapeutic area | Infection Prevention / Dermatology |
| Phase | FDA-approved |
Mechanism of action
Chlorhexidine gluconate works by binding to negatively charged bacterial cell membranes, causing leakage of cellular contents and cell death. It is bactericidal at higher concentrations and bacteriostatic at lower concentrations, with activity against a wide range of gram-positive and gram-negative bacteria, as well as some fungi and viruses. As a topical antiseptic body cleanser, it reduces microbial load on skin surfaces.
Approved indications
- Antiseptic skin cleansing and preoperative skin preparation
- Prevention of skin and wound infections
Common side effects
- Skin irritation or sensitization
- Contact dermatitis
- Allergic reaction
Key clinical trials
- Bacterial Decolonization Plus Intraoperative Angiography for Soft Tissue Sarcomas Receiving Preoperative Radiotherapy (CONCERTO) (PHASE2)
- Study of 2% Chlorhexidine Gluconate-Impregnated Bath Cloths to Prevent MRSA Colonization in Complex Continuing Care (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- CHG antiseptic body cleanser CI brief — competitive landscape report
- CHG antiseptic body cleanser updates RSS · CI watch RSS
- Baycrest portfolio CI