{"id":"chg-antiseptic-body-cleanser","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation or sensitization"},{"rate":null,"effect":"Contact dermatitis"},{"rate":null,"effect":"Allergic reaction"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Chlorhexidine gluconate works by binding to negatively charged bacterial cell membranes, causing leakage of cellular contents and cell death. It is bactericidal at higher concentrations and bacteriostatic at lower concentrations, with activity against a wide range of gram-positive and gram-negative bacteria, as well as some fungi and viruses. As a topical antiseptic body cleanser, it reduces microbial load on skin surfaces.","oneSentence":"CHG (chlorhexidine gluconate) is an antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, providing broad-spectrum antiseptic activity.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:29:18.911Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Antiseptic skin cleansing and preoperative skin preparation"},{"name":"Prevention of skin and wound infections"}]},"trialDetails":[{"nctId":"NCT06712433","phase":"PHASE2","title":"Bacterial Decolonization Plus Intraoperative Angiography for Soft Tissue Sarcomas Receiving Preoperative Radiotherapy (CONCERTO)","status":"NOT_YET_RECRUITING","sponsor":"Adam Olson","startDate":"2026-09-30","conditions":"Sarcoma,Soft Tissue","enrollment":31},{"nctId":"NCT01717690","phase":"PHASE4","title":"Study of 2% Chlorhexidine Gluconate-Impregnated Bath Cloths to Prevent MRSA Colonization in Complex Continuing Care","status":"COMPLETED","sponsor":"Baycrest","startDate":"2013-08","conditions":"Staph Aureus Methicillin Resistant Colonization","enrollment":122}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Chlorhexidine gluconate cloths","Drug Identification Number (Health Canada): 02245741"],"phase":"marketed","status":"active","brandName":"CHG antiseptic body cleanser","genericName":"CHG antiseptic body cleanser","companyName":"Baycrest","companyId":"baycrest","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CHG (chlorhexidine gluconate) is an antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, providing broad-spectrum antiseptic activity. Used for Antiseptic skin cleansing and preoperative skin preparation, Prevention of skin and wound infections.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}