Last reviewed · How we verify
Calogen®
Calogen is a high-calorie, high-fat oral nutritional supplement that provides concentrated energy to support weight maintenance and nutritional status in patients with increased caloric requirements.
Calogen is a high-calorie, high-fat oral nutritional supplement that provides concentrated energy to support weight maintenance and nutritional status in patients with increased caloric requirements. Used for Nutritional support in patients with malnutrition or cachexia, Caloric supplementation in patients with increased energy requirements, Nutritional support in cancer patients, post-surgical patients, and those with chronic disease.
At a glance
| Generic name | Calogen® |
|---|---|
| Sponsor | Merck Sharp & Dohme LLC |
| Drug class | Nutritional supplement |
| Modality | Small molecule |
| Therapeutic area | Nutrition/Supportive Care |
| Phase | FDA-approved |
Mechanism of action
Calogen delivers 4.5 kcal/mL through a lipid-based emulsion, allowing patients to meet elevated energy needs in smaller volumes. It is designed for patients with malnutrition, cachexia, or conditions requiring increased caloric intake who may have limited oral intake capacity. The formulation is typically used as a supplement to standard diet or as a sole source of nutrition in clinical settings.
Approved indications
- Nutritional support in patients with malnutrition or cachexia
- Caloric supplementation in patients with increased energy requirements
- Nutritional support in cancer patients, post-surgical patients, and those with chronic disease
Common side effects
- Gastrointestinal upset
- Diarrhea
- Nausea
- Lipemia (elevated blood lipids)
Key clinical trials
- Dietary Interventions During Living Kidney Donations (NA)
- Networks of Bacterium-Metabolite Interactions in the Small Intestine (NA)
- A Pharmacokinetic Analysis of Posaconazole in Lung Transplant Recipients (MK-5592-105) (PHASE4)
- Energy Dense Oleic Acid Formula to Geriatric Patients (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Calogen® CI brief — competitive landscape report
- Calogen® updates RSS · CI watch RSS
- Merck Sharp & Dohme LLC portfolio CI