{"id":"calogen","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Lipemia (elevated blood lipids)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Calogen delivers 4.5 kcal/mL through a lipid-based emulsion, allowing patients to meet elevated energy needs in smaller volumes. It is designed for patients with malnutrition, cachexia, or conditions requiring increased caloric intake who may have limited oral intake capacity. The formulation is typically used as a supplement to standard diet or as a sole source of nutrition in clinical settings.","oneSentence":"Calogen is a high-calorie, high-fat oral nutritional supplement that provides concentrated energy to support weight maintenance and nutritional status in patients with increased caloric requirements.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:29:39.932Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Nutritional support in patients with malnutrition or cachexia"},{"name":"Caloric supplementation in patients with increased energy requirements"},{"name":"Nutritional support in cancer patients, post-surgical patients, and those with chronic disease"}]},"trialDetails":[{"nctId":"NCT05709600","phase":"NA","title":"Dietary Interventions During Living Kidney Donations","status":"RECRUITING","sponsor":"University of Cologne","startDate":"2023-02-01","conditions":"Living-Kidney Donors","enrollment":80},{"nctId":"NCT04978077","phase":"NA","title":"Networks of Bacterium-Metabolite Interactions in the Small Intestine","status":"TERMINATED","sponsor":"Insel Gruppe AG, University Hospital Bern","startDate":"2021-12-16","conditions":"Diet, Healthy, Microbial Colonization","enrollment":120},{"nctId":"NCT01667107","phase":"PHASE4","title":"A Pharmacokinetic Analysis of Posaconazole in Lung Transplant Recipients (MK-5592-105)","status":"TERMINATED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2013-01-23","conditions":"Fungal Infection","enrollment":26},{"nctId":"NCT01042340","phase":"NA","title":"Energy Dense Oleic Acid Formula to Geriatric Patients","status":"COMPLETED","sponsor":"Karolinska University Hospital","startDate":"2005-12","conditions":"Nutritional Intervention","enrollment":71}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":15,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Calogen®","genericName":"Calogen®","companyName":"Merck Sharp & Dohme LLC","companyId":"merck-sharp-dohme-llc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Calogen is a high-calorie, high-fat oral nutritional supplement that provides concentrated energy to support weight maintenance and nutritional status in patients with increased caloric requirements. Used for Nutritional support in patients with malnutrition or cachexia, Caloric supplementation in patients with increased energy requirements, Nutritional support in cancer patients, post-surgical patients, and those with chronic disease.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}