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Calmoseptine Ointment
Calmoseptine Ointment creates a protective barrier on skin while providing antimicrobial and anti-inflammatory effects to promote wound healing and prevent infection.
Calmoseptine Ointment creates a protective barrier on skin while providing antimicrobial and anti-inflammatory effects to promote wound healing and prevent infection. Used for Diaper dermatitis and nappy rash, Minor cuts, abrasions, and skin irritations, Pressure ulcer prevention and treatment.
At a glance
| Generic name | Calmoseptine Ointment |
|---|---|
| Also known as | Calmoseptine |
| Sponsor | University of the Philippines |
| Drug class | Topical antimicrobial and protective ointment |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Mechanism of action
The ointment combines a water-repellent base with bismuth subnitrate and zinc oxide to form a protective layer against moisture and irritants. It has antimicrobial properties that help prevent bacterial colonization of wounds while reducing inflammation and promoting epithelialization of damaged skin.
Approved indications
- Diaper dermatitis and nappy rash
- Minor cuts, abrasions, and skin irritations
- Pressure ulcer prevention and treatment
- Incontinence-associated dermatitis
Common side effects
- Local skin irritation or sensitization
- Allergic contact dermatitis
Key clinical trials
- Trial Comparing Calmoseptine Ointment and Desitin Diaper Rash Paste in Diaper Dermatitis in Neonates and Infants (PHASE4)
- Treatment of Incontinence Associated Dermatitis in Older Children and Adults (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Calmoseptine Ointment CI brief — competitive landscape report
- Calmoseptine Ointment updates RSS · CI watch RSS
- University of the Philippines portfolio CI