{"id":"calmoseptine-ointment","safety":{"commonSideEffects":[{"rate":null,"effect":"Local skin irritation or sensitization"},{"rate":null,"effect":"Allergic contact dermatitis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The ointment combines a water-repellent base with bismuth subnitrate and zinc oxide to form a protective layer against moisture and irritants. It has antimicrobial properties that help prevent bacterial colonization of wounds while reducing inflammation and promoting epithelialization of damaged skin.","oneSentence":"Calmoseptine Ointment creates a protective barrier on skin while providing antimicrobial and anti-inflammatory effects to promote wound healing and prevent infection.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:29:39.944Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Diaper dermatitis and nappy rash"},{"name":"Minor cuts, abrasions, and skin irritations"},{"name":"Pressure ulcer prevention and treatment"},{"name":"Incontinence-associated dermatitis"}]},"trialDetails":[{"nctId":"NCT02716415","phase":"PHASE4","title":"Trial Comparing Calmoseptine Ointment and Desitin Diaper Rash Paste in Diaper Dermatitis in Neonates and Infants","status":"COMPLETED","sponsor":"University of the Philippines","startDate":"2015-03","conditions":"Diaper Dermatitis","enrollment":319},{"nctId":"NCT02080247","phase":"PHASE3","title":"Treatment of Incontinence Associated Dermatitis in Older Children and Adults","status":"COMPLETED","sponsor":"University of the Philippines","startDate":"2012-12","conditions":"Incontinence Associated Dermatitis","enrollment":142}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":634,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Calmoseptine"],"phase":"marketed","status":"active","brandName":"Calmoseptine Ointment","genericName":"Calmoseptine Ointment","companyName":"University of the Philippines","companyId":"university-of-the-philippines","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Calmoseptine Ointment creates a protective barrier on skin while providing antimicrobial and anti-inflammatory effects to promote wound healing and prevent infection. Used for Diaper dermatitis and nappy rash, Minor cuts, abrasions, and skin irritations, Pressure ulcer prevention and treatment.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}