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calcium phosphosilicate putty alloplast graft
Calcium phosphosilicate putty acts as an osteoconductive and osteoinductive bone graft substitute that promotes bone regeneration and healing in dental and orthopedic applications.
Calcium phosphosilicate putty acts as an osteoconductive and osteoinductive bone graft substitute that promotes bone regeneration and healing in dental and orthopedic applications. Used for Bone defect filling in dental and orthopedic surgery, Periodontal bone regeneration, Alveolar bone augmentation.
At a glance
| Generic name | calcium phosphosilicate putty alloplast graft |
|---|---|
| Also known as | NovaBone, Osteogenics |
| Sponsor | University of Louisville |
| Drug class | Bone graft substitute |
| Modality | Biologic |
| Therapeutic area | Orthopedics/Dentistry |
| Phase | FDA-approved |
Mechanism of action
This alloplast material provides a biocompatible scaffold that facilitates new bone formation through osteoconduction (physical guidance of bone growth along the material surface) and osteoinduction (stimulation of osteogenic cells). The calcium phosphosilicate composition releases ions that promote mineralization and integrate with native bone tissue, serving as a resorbable matrix that is gradually replaced by new bone.
Approved indications
- Bone defect filling in dental and orthopedic surgery
- Periodontal bone regeneration
- Alveolar bone augmentation
Common side effects
- Minimal adverse events reported
- Potential for material displacement
- Infection at surgical site
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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