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Bupivacaine-fentanyl

Abdelrady S Ibrahim, MD · FDA-approved active Small molecule

Bupivacaine-fentanyl is a Local anesthetic-opioid combination Small molecule drug developed by Abdelrady S Ibrahim, MD. It is currently FDA-approved for Regional anesthesia and analgesia for surgical procedures, Postoperative pain management. Also known as: Epidural Catheter insertion, Spinal Anesthesia, Marcaine, Sensorcaine.

Bupivacaine-fentanyl is a combination of a local anesthetic and an opioid analgesic that blocks nerve conduction and provides pain relief through multiple mechanisms.

Bupivacaine-fentanyl is a combination anesthetic and analgesic used primarily for regional anesthesia and pain management. Despite no FDA label, it is widely studied in various surgical and labor settings, showing promise in reducing postoperative pain and improving patient outcomes.

At a glance

Generic nameBupivacaine-fentanyl
Also known asEpidural Catheter insertion, Spinal Anesthesia, Marcaine, Sensorcaine, Astra Zeneca
SponsorAbdelrady S Ibrahim, MD
Drug classLocal anesthetic-opioid combination
TargetVoltage-gated sodium channels (bupivacaine); mu-opioid receptor (fentanyl)
ModalitySmall molecule
Therapeutic areaAnesthesia and Pain Management
PhaseFDA-approved

Mechanism of action

Bupivacaine is a long-acting amide local anesthetic that blocks sodium channels in nerve fibers, preventing action potential propagation and numbing sensation in a localized area. Fentanyl is a potent synthetic opioid that binds to mu-opioid receptors in the central and peripheral nervous system to provide additional analgesia. Together, they provide synergistic pain relief for regional anesthesia and analgesia.

Approved indications

Common side effects

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Frequently asked questions about Bupivacaine-fentanyl

What is Bupivacaine-fentanyl?

Bupivacaine-fentanyl is a Local anesthetic-opioid combination drug developed by Abdelrady S Ibrahim, MD, indicated for Regional anesthesia and analgesia for surgical procedures, Postoperative pain management.

How does Bupivacaine-fentanyl work?

Bupivacaine-fentanyl is a combination of a local anesthetic and an opioid analgesic that blocks nerve conduction and provides pain relief through multiple mechanisms.

What is Bupivacaine-fentanyl used for?

Bupivacaine-fentanyl is indicated for Regional anesthesia and analgesia for surgical procedures, Postoperative pain management.

Who makes Bupivacaine-fentanyl?

Bupivacaine-fentanyl is developed and marketed by Abdelrady S Ibrahim, MD (see full Abdelrady S Ibrahim, MD pipeline at /company/abdelrady-s-ibrahim-md).

Is Bupivacaine-fentanyl also known as anything else?

Bupivacaine-fentanyl is also known as Epidural Catheter insertion, Spinal Anesthesia, Marcaine, Sensorcaine, Astra Zeneca.

What drug class is Bupivacaine-fentanyl in?

Bupivacaine-fentanyl belongs to the Local anesthetic-opioid combination class. See all Local anesthetic-opioid combination drugs at /class/local-anesthetic-opioid-combination.

What development phase is Bupivacaine-fentanyl in?

Bupivacaine-fentanyl is FDA-approved (marketed).

What are the side effects of Bupivacaine-fentanyl?

Common side effects of Bupivacaine-fentanyl include Hypotension, Bradycardia, Respiratory depression, Nausea, Dizziness, Headache.

What does Bupivacaine-fentanyl target?

Bupivacaine-fentanyl targets Voltage-gated sodium channels (bupivacaine); mu-opioid receptor (fentanyl) and is a Local anesthetic-opioid combination.

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