Last reviewed 2026-04-22 · How we verify

BTOS-HA

BTOS-HA is a hyaluronic acid-based ophthalmic formulation designed to provide sustained lubrication and protection to the ocular surface.

BTOS-HA is a hyaluronic acid-based ophthalmic formulation designed to provide sustained lubrication and protection to the ocular surface. Used for Dry eye disease / Keratoconjunctivitis sicca.

At a glance

Mechanism of action

BTOS-HA utilizes hyaluronic acid, a naturally occurring polysaccharide with high water-binding capacity, to maintain corneal hydration and reduce friction on the ocular surface. The formulation is intended to provide prolonged tear film stability and protect against dry eye symptoms by maintaining a protective barrier on the cornea and conjunctiva.

Approved indications

• Dry eye disease / Keratoconjunctivitis sicca

Common side effects

• Ocular irritation
• Blurred vision
• Eye discomfort

Key clinical trials

• A Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% With Sodium Hyaluronate Relative to Lumify in Adult Subjects With Ocular Redness (PHASE3)

Primary sources

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