{"id":"btos-ha","safety":{"commonSideEffects":[{"rate":null,"effect":"Ocular irritation"},{"rate":null,"effect":"Blurred vision"},{"rate":null,"effect":"Eye discomfort"}]},"_chembl":{"chemblId":"CHEMBL1564377","moleculeType":"Small molecule","molecularWeight":"116.12"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"BTOS-HA utilizes hyaluronic acid, a naturally occurring polysaccharide with high water-binding capacity, to maintain corneal hydration and reduce friction on the ocular surface. The formulation is intended to provide prolonged tear film stability and protect against dry eye symptoms by maintaining a protective barrier on the cornea and conjunctiva.","oneSentence":"BTOS-HA is a hyaluronic acid-based ophthalmic formulation designed to provide sustained lubrication and protection to the ocular surface.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:53:46.605Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye disease / Keratoconjunctivitis sicca"}]},"trialDetails":[{"nctId":"NCT06803654","phase":"PHASE3","title":"A Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% With Sodium Hyaluronate Relative to Lumify in Adult Subjects With Ocular Redness","status":"COMPLETED","sponsor":"Bausch & Lomb Incorporated","startDate":"2025-05-22","conditions":"Ocular Redness","enrollment":578}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"BTOS-HA","genericName":"BTOS-HA","companyName":"Bausch & Lomb Incorporated","companyId":"bausch-lomb-incorporated","modality":"Small molecule","firstApprovalDate":"","aiSummary":"BTOS-HA is a hyaluronic acid-based ophthalmic formulation designed to provide sustained lubrication and protection to the ocular surface. Used for Dry eye disease / Keratoconjunctivitis sicca.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}