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Brisement injection
Brisement is a procedure involving forceful manipulation and injection of fluid into a stiff joint to break adhesions and restore mobility.
Brisement is a procedure involving forceful manipulation and injection of fluid into a stiff joint to break adhesions and restore mobility. Used for Adhesive capsulitis (frozen shoulder), Joint stiffness and restricted range of motion.
At a glance
| Generic name | Brisement injection |
|---|---|
| Sponsor | Brigham and Women's Hospital |
| Modality | Biologic |
| Therapeutic area | Orthopedics/Rheumatology |
| Phase | FDA-approved |
Mechanism of action
Brisement sous anesthésie (breaking under anesthesia) is a mechanical intervention where saline or anesthetic solution is injected into a joint capsule under pressure to disrupt fibrous adhesions and scar tissue that restrict movement. This is typically performed under general or regional anesthesia to allow forceful manipulation of the joint without patient guarding. The procedure aims to restore range of motion in frozen or stiff joints.
Approved indications
- Adhesive capsulitis (frozen shoulder)
- Joint stiffness and restricted range of motion
Common side effects
- Pain and swelling post-procedure
- Temporary increased stiffness
- Hematoma or bruising
- Infection (rare)
Key clinical trials
- The Efficacy of Brisement Compared to Physical Therapy for the Treatment of Achilles Tendinosis (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Brisement injection CI brief — competitive landscape report
- Brisement injection updates RSS · CI watch RSS
- Brigham and Women's Hospital portfolio CI