{"id":"brisement-injection","safety":{"commonSideEffects":[{"rate":null,"effect":"Pain and swelling post-procedure"},{"rate":null,"effect":"Temporary increased stiffness"},{"rate":null,"effect":"Hematoma or bruising"},{"rate":null,"effect":"Infection (rare)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Brisement sous anesthésie (breaking under anesthesia) is a mechanical intervention where saline or anesthetic solution is injected into a joint capsule under pressure to disrupt fibrous adhesions and scar tissue that restrict movement. This is typically performed under general or regional anesthesia to allow forceful manipulation of the joint without patient guarding. The procedure aims to restore range of motion in frozen or stiff joints.","oneSentence":"Brisement is a procedure involving forceful manipulation and injection of fluid into a stiff joint to break adhesions and restore mobility.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:28:52.071Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Adhesive capsulitis (frozen shoulder)"},{"name":"Joint stiffness and restricted range of motion"}]},"trialDetails":[{"nctId":"NCT03363789","phase":"PHASE4","title":"The Efficacy of Brisement Compared to Physical Therapy for the Treatment of Achilles Tendinosis","status":"WITHDRAWN","sponsor":"Brigham and Women's Hospital","startDate":"2018-02-01","conditions":"Achilles Tendinopathy","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Brisement injection","genericName":"Brisement injection","companyName":"Brigham and Women's Hospital","companyId":"brigham-and-women-s-hospital","modality":"Biologic","firstApprovalDate":"","aiSummary":"Brisement is a procedure involving forceful manipulation and injection of fluid into a stiff joint to break adhesions and restore mobility. Used for Adhesive capsulitis (frozen shoulder), Joint stiffness and restricted range of motion.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}