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brand name metoprolol ER
Metoprolol ER is a beta-1 selective adrenergic receptor antagonist that reduces heart rate and blood pressure by blocking the effects of norepinephrine and epinephrine on the heart.
Metoprolol ER is a beta-1 selective adrenergic receptor antagonist that reduces heart rate and blood pressure by blocking the effects of norepinephrine and epinephrine on the heart. Used for Hypertension, Angina pectoris, Myocardial infarction (post-MI management).
At a glance
| Generic name | brand name metoprolol ER |
|---|---|
| Also known as | Metoprolol extended-release (ER) |
| Sponsor | University of Florida |
| Drug class | Beta-1 selective adrenergic receptor antagonist (beta-blocker) |
| Target | Beta-1 adrenergic receptor |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
Metoprolol selectively blocks beta-1 adrenergic receptors on cardiac tissue, decreasing heart contractility and heart rate. This reduces myocardial oxygen demand and lowers blood pressure. The extended-release formulation provides sustained drug delivery over 24 hours, allowing once-daily dosing for improved patient compliance in chronic cardiovascular conditions.
Approved indications
- Hypertension
- Angina pectoris
- Myocardial infarction (post-MI management)
- Heart failure
- Atrial fibrillation (rate control)
Common side effects
- Fatigue
- Dizziness
- Bradycardia
- Hypotension
- Depression
- Sexual dysfunction
- Bronchospasm (in susceptible patients)
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- brand name metoprolol ER CI brief — competitive landscape report
- brand name metoprolol ER updates RSS · CI watch RSS
- University of Florida portfolio CI