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Botulinum Toxin Type A Injection [Xeomin]
Botulinum Toxin Type A Injection [Xeomin] is a Neuromuscular blocking agent Small molecule drug developed by Assistance Publique - Hôpitaux de Paris. It is currently in Phase 3 development for Cervical dystonia, Blepharospasm, Hemifacial spasm. Also known as: Xeomin.
Botulinum toxin type A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis.
Botulinum toxin type A blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis. Used for Cervical dystonia, Blepharospasm, Hemifacial spasm.
At a glance
| Generic name | Botulinum Toxin Type A Injection [Xeomin] |
|---|---|
| Also known as | Xeomin |
| Sponsor | Assistance Publique - Hôpitaux de Paris |
| Drug class | Neuromuscular blocking agent |
| Target | SNAP-25 (synaptosome-associated protein of 25 kDa) |
| Modality | Small molecule |
| Therapeutic area | Neurology; Aesthetics |
| Phase | Phase 3 |
Mechanism of action
Xeomin is a purified botulinum toxin type A that irreversibly cleaves SNAP-25, a protein essential for acetylcholine vesicle fusion and release at the neuromuscular junction. This prevents muscle contraction in the injected area. The effect is temporary, lasting 3-4 months, after which nerve terminals regenerate and muscle function returns.
Approved indications
- Cervical dystonia
- Blepharospasm
- Hemifacial spasm
- Glabellar lines (aesthetic indication)
- Chronic migraine
Common side effects
- Headache
- Neck pain
- Injection site pain
- Muscle weakness
- Eyelid ptosis
- Dysphagia
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Botulinum Toxin Type A Injection [Xeomin] CI brief — competitive landscape report
- Botulinum Toxin Type A Injection [Xeomin] updates RSS · CI watch RSS
- Assistance Publique - Hôpitaux de Paris portfolio CI
Frequently asked questions about Botulinum Toxin Type A Injection [Xeomin]
What is Botulinum Toxin Type A Injection [Xeomin]?
How does Botulinum Toxin Type A Injection [Xeomin] work?
What is Botulinum Toxin Type A Injection [Xeomin] used for?
Who makes Botulinum Toxin Type A Injection [Xeomin]?
Is Botulinum Toxin Type A Injection [Xeomin] also known as anything else?
What drug class is Botulinum Toxin Type A Injection [Xeomin] in?
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What does Botulinum Toxin Type A Injection [Xeomin] target?
Related
- Drug class: All Neuromuscular blocking agent drugs
- Target: All drugs targeting SNAP-25 (synaptosome-associated protein of 25 kDa)
- Manufacturer: Assistance Publique - Hôpitaux de Paris — full pipeline
- Therapeutic area: All drugs in Neurology; Aesthetics
- Indication: Drugs for Cervical dystonia
- Indication: Drugs for Blepharospasm
- Indication: Drugs for Hemifacial spasm
- Also known as: Xeomin
- Compare: Botulinum Toxin Type A Injection [Xeomin] vs similar drugs
- Pricing: Botulinum Toxin Type A Injection [Xeomin] cost, discount & access