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beta-1,3-glucan
beta-1,3-glucan is a Immunostimulant / Biological response modifier Small molecule drug developed by Meiji University of Oriental Medicine. It is currently FDA-approved for Cancer immunotherapy (adjunctive), Immune enhancement in infectious diseases.
Beta-1,3-glucan is a polysaccharide that activates innate immune cells, particularly macrophages and neutrophils, to enhance immune response and promote anti-tumor or anti-infection activity.
Beta-1,3-glucan is a polysaccharide that activates innate immune cells, particularly macrophages and neutrophils, to enhance immune response and promote anti-tumor or anti-infection activity. Used for Cancer immunotherapy (adjunctive), Immune enhancement in infectious diseases.
At a glance
| Generic name | beta-1,3-glucan |
|---|---|
| Sponsor | Meiji University of Oriental Medicine |
| Drug class | Immunostimulant / Biological response modifier |
| Target | Dectin-1 (and other pattern recognition receptors) |
| Modality | Small molecule |
| Therapeutic area | Immunology / Oncology |
| Phase | FDA-approved |
Mechanism of action
Beta-1,3-glucan is a fungal cell wall-derived polysaccharide that binds to pattern recognition receptors (such as Dectin-1) on immune cells, triggering innate immune activation. This leads to enhanced phagocytosis, cytokine production, and natural killer cell activity, supporting immune surveillance against pathogens and potentially malignant cells.
Approved indications
- Cancer immunotherapy (adjunctive)
- Immune enhancement in infectious diseases
Common side effects
- Fever
- Injection site reactions
- Mild gastrointestinal disturbance
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- beta-1,3-glucan CI brief — competitive landscape report
- beta-1,3-glucan updates RSS · CI watch RSS
- Meiji University of Oriental Medicine portfolio CI
Frequently asked questions about beta-1,3-glucan
What is beta-1,3-glucan?
How does beta-1,3-glucan work?
What is beta-1,3-glucan used for?
Who makes beta-1,3-glucan?
What drug class is beta-1,3-glucan in?
What development phase is beta-1,3-glucan in?
What are the side effects of beta-1,3-glucan?
What does beta-1,3-glucan target?
Related
- Drug class: All Immunostimulant / Biological response modifier drugs
- Target: All drugs targeting Dectin-1 (and other pattern recognition receptors)
- Manufacturer: Meiji University of Oriental Medicine — full pipeline
- Therapeutic area: All drugs in Immunology / Oncology
- Indication: Drugs for Cancer immunotherapy (adjunctive)
- Indication: Drugs for Immune enhancement in infectious diseases
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing