Last reviewed · How we verify
Benzoyl peroxide and sulfur
Benzoyl peroxide and sulfur work together to reduce acne by killing acne-causing bacteria, reducing sebum production, and promoting skin cell turnover.
Benzoyl peroxide and sulfur work together to reduce acne by killing acne-causing bacteria, reducing sebum production, and promoting skin cell turnover. Used for Acne vulgaris.
At a glance
| Generic name | Benzoyl peroxide and sulfur |
|---|---|
| Sponsor | Zurita Laboratorio Farmaceutico Ltda. |
| Drug class | Topical acne treatment combination |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Mechanism of action
Benzoyl peroxide is a potent antimicrobial and keratolytic agent that generates reactive oxygen species to eliminate Cutibacterium acnes (formerly Propionibacterium acnes) and exfoliates dead skin cells. Sulfur acts as a mild keratolytic and antimicrobial agent that helps unclog pores and reduce sebaceous gland activity. Together, they address multiple pathogenic factors in acne formation.
Approved indications
- Acne vulgaris
Common side effects
- Skin irritation
- Dryness
- Erythema
- Peeling
- Contact dermatitis
Key clinical trials
- Patients Response to Early Switch To Oral:Osteomyelitis Study (EARLY_PHASE1)
- Study to Determine and Compare the Tolerance and Irritation Potential of Topical Acne Medications (PHASE4)
- A Study That Evaluates the Decrease in Irritation When Using Additional Acne Treatment Products (PHASE4)
- Clinical Study to Evaluate the Efficacy of Topical Medications Containing Benzoyl Peroxide and Sulfur in the Regression in the Short Time (24 Hours) of Moderate Acne Vulgaris Grade II (Pimples) (PHASE4)
- Safety and Efficacy Study of Acnase Creme in the Treatment of Acne Vulgaris I and II (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Benzoyl peroxide and sulfur CI brief — competitive landscape report
- Benzoyl peroxide and sulfur updates RSS · CI watch RSS
- Zurita Laboratorio Farmaceutico Ltda. portfolio CI