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AVE2268

Sanofi · Phase 2 active Small molecule

AVE2268 is a small molecule that targets the SGLT2 receptor.

AVE2268 is a small molecule that targets the SGLT2 receptor. Used for Type 2 diabetes.

At a glance

Generic nameAVE2268
SponsorSanofi
Drug classSGLT2 inhibitor
TargetSGLT2
ModalitySmall molecule
Therapeutic areaDiabetes
PhasePhase 2

Mechanism of action

AVE2268 works by inhibiting the SGLT2 receptor, which reduces glucose reabsorption in the kidneys and lowers blood glucose levels. This mechanism is similar to other SGLT2 inhibitors, such as canagliflozin and empagliflozin. By reducing glucose reabsorption, AVE2268 helps to improve glycemic control in patients with type 2 diabetes.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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