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Atrovent + Bricanyl or Atrovent + Ventoline

University Hospital, Tours · FDA-approved active Small molecule

This combination pairs an anticholinergic bronchodilator with a beta-2 agonist bronchodilator to relax airway smooth muscle through dual pathways.

This combination pairs an anticholinergic bronchodilator with a beta-2 agonist bronchodilator to relax airway smooth muscle through dual pathways. Used for Chronic obstructive pulmonary disease (COPD), Asthma (acute exacerbation or maintenance therapy).

At a glance

Generic nameAtrovent + Bricanyl or Atrovent + Ventoline
SponsorUniversity Hospital, Tours
Drug classCombination bronchodilator (anticholinergic + beta-2 agonist)
TargetMuscarinic acetylcholine receptors (M3) and beta-2 adrenergic receptor
ModalitySmall molecule
Therapeutic areaRespiratory/Pulmonology
PhaseFDA-approved

Mechanism of action

Atrovent (ipratropium) blocks muscarinic acetylcholine receptors to prevent bronchoconstriction, while Bricanyl (terbutaline) or Ventoline (albuterol/salbutamol) activates beta-2 adrenergic receptors to promote bronchodilation. Together, they provide complementary mechanisms for rapid and sustained airway opening in obstructive airway disease.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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