{"id":"atrovent-bricanyl-or-atrovent-ventoline","safety":{"commonSideEffects":[{"rate":null,"effect":"Tremor"},{"rate":null,"effect":"Tachycardia"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Dry mouth"},{"rate":null,"effect":"Nervousness/anxiety"}]},"_chembl":{"chemblId":"CHEMBL2134724","moleculeType":"Small molecule","molecularWeight":"430.38"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Atrovent (ipratropium) blocks muscarinic acetylcholine receptors to prevent bronchoconstriction, while Bricanyl (terbutaline) or Ventoline (albuterol/salbutamol) activates beta-2 adrenergic receptors to promote bronchodilation. Together, they provide complementary mechanisms for rapid and sustained airway opening in obstructive airway disease.","oneSentence":"This combination pairs an anticholinergic bronchodilator with a beta-2 agonist bronchodilator to relax airway smooth muscle through dual pathways.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:19:39.822Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Chronic obstructive pulmonary disease (COPD)"},{"name":"Asthma (acute exacerbation or maintenance therapy)"}]},"trialDetails":[{"nctId":"NCT02103374","phase":"PHASE4","title":"Evaluation of Benefit of Nebulized Bronchodilators at Home in Severe Chronic Obstructive Pulmonary Disease and Very Severe Steady State","status":"COMPLETED","sponsor":"University Hospital, Tours","startDate":"2012-01","conditions":"Severe Chronic Obstructive Pulmonary Disease","enrollment":45}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":119,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Atrovent + Bricanyl or Atrovent + Ventoline","genericName":"Atrovent + Bricanyl or Atrovent + Ventoline","companyName":"University Hospital, Tours","companyId":"university-hospital-tours","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This combination pairs an anticholinergic bronchodilator with a beta-2 agonist bronchodilator to relax airway smooth muscle through dual pathways. Used for Chronic obstructive pulmonary disease (COPD), Asthma (acute exacerbation or maintenance therapy).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}