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Amsalog (asulacrine)

unknown active ✓ Verified May 2026

Amsalog (generic name: asulacrine) is a asulacrine drug. It is currently in unknown development.

Amsalog works by blocking the enzyme DNA topoisomerase 2-alpha, which is essential for DNA replication and repair.

Amsalog is a small molecule. It is also known by other names, including Asulacrine, CI-921, NSC 343499, and SN-21407.

At a glance

Generic nameasulacrine
Drug classasulacrine
TargetDNA topoisomerase 2-alpha
Therapeutic areaOncology
Phaseunknown

Mechanism of action

Imagine your DNA is a long, twisted ladder. DNA topoisomerase 2-alpha is like a special tool that helps untwist the ladder so that the DNA can be copied. Amsalog blocks this tool, which can prevent cancer cells from growing and dividing.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Amsalog

What is Amsalog?

Amsalog (asulacrine) is a asulacrine drug.

How does Amsalog work?

Amsalog works by blocking the enzyme DNA topoisomerase 2-alpha, which is essential for DNA replication and repair.

What is the generic name of Amsalog?

asulacrine is the generic (nonproprietary) name of Amsalog.

What drug class is Amsalog in?

Amsalog belongs to the asulacrine class. See all asulacrine drugs at /class/asulacrine.

What development phase is Amsalog in?

Amsalog is in unknown.

What does Amsalog target?

Amsalog targets DNA topoisomerase 2-alpha and is a asulacrine.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing