Last reviewed 2026-05-15 · How we verify

Ascorbic acid-Vitamin B1-Hydrocortisone

Ascorbic acid-Vitamin B1-Hydrocortisone is a Combination vitamin and corticosteroid supplement Small molecule drug developed by Far Eastern Memorial Hospital. It is currently FDA-approved for Nutritional supplementation and anti-inflammatory support in hospitalized or acutely ill patients, Adjunctive therapy for conditions requiring corticosteroid and micronutrient support.

This combination provides anti-inflammatory, immune support, and antioxidant effects through hydrocortisone's glucocorticoid action, vitamin B1's cofactor role in metabolism, and ascorbic acid's antioxidant properties.

This combination provides anti-inflammatory, immune support, and antioxidant effects through hydrocortisone's glucocorticoid action, vitamin B1's cofactor role in metabolism, and ascorbic acid's antioxidant properties. Used for Nutritional supplementation and anti-inflammatory support in hospitalized or acutely ill patients, Adjunctive therapy for conditions requiring corticosteroid and micronutrient support.

At a glance

Mechanism of action

Hydrocortisone suppresses inflammatory and immune responses by binding glucocorticoid receptors. Ascorbic acid (vitamin C) acts as an antioxidant and cofactor for collagen synthesis and immune function. Vitamin B1 (thiamine) serves as a coenzyme in carbohydrate and energy metabolism. Together, these agents provide symptomatic relief and support recovery in conditions involving inflammation, oxidative stress, and metabolic demand.

Approved indications

• Nutritional supplementation and anti-inflammatory support in hospitalized or acutely ill patients
• Adjunctive therapy for conditions requiring corticosteroid and micronutrient support

Common side effects

• Hyperglycemia
• Immunosuppression
• Gastrointestinal upset
• Insomnia or mood changes

Key clinical trials

• Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors (PHASE2)
• Effects of Intravenous Metabolic Recovery Agent in Elderly Septic Patients on Prognosis and Microcirculation. (NA)
• Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock (PHASE1, PHASE2)
• Vitamin C, Hydrocortisone and Thiamine for Septic Shock (PHASE2)
• Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic Shock (NA)
• HAT for the Treatment of Sepsis Associated With NASTI (PHASE1, PHASE2)
• Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock (PHASE3)
• Blessing or Curse? Combined Vitamin Therapy in Non Viral Septic Shock. (PHASE4)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• Ascorbic acid-Vitamin B1-Hydrocortisone CI brief — competitive landscape report
• Ascorbic acid-Vitamin B1-Hydrocortisone updates RSS · CI watch RSS
• Far Eastern Memorial Hospital portfolio CI

Frequently asked questions about Ascorbic acid-Vitamin B1-Hydrocortisone

Related

• Drug class: All Combination vitamin and corticosteroid supplement drugs
• Manufacturer: Far Eastern Memorial Hospital — full pipeline
• Therapeutic area: All drugs in Supportive care / General health
• Indication: Drugs for Nutritional supplementation and anti-inflammatory support in hospitalized or acutely ill patients
• Indication: Drugs for Adjunctive therapy for conditions requiring corticosteroid and micronutrient support

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing