Last reviewed 2026-06-01 · How we verify

Arvekap, Pregnyl

Eugonia · FDA-approved active Small molecule Under review

Arvekap, Pregnyl is a Gonadotropin; human chorionic gonadotropin (hCG) Small molecule drug developed by Eugonia. It is currently FDA-approved for Induction of ovulation in anovulatory infertile women, Treatment of hypogonadism in males, Cryptorchidism (undescended testis) in prepubertal boys.

Pregnyl is a human chorionic gonadotropin (hCG) that stimulates the production of sex hormones by acting on gonadal tissue.

Arvekap and Pregnyl are interventions used to study infertility, specifically in a clinical trial comparing their effectiveness for ovulation induction in patients with high response to IVF drugs. Arvekap is a protein modality, which is also known by other names including Decapeptyl.

At a glance

Generic name	Arvekap, Pregnyl
Sponsor	Eugonia
Drug class	Gonadotropin; human chorionic gonadotropin (hCG)
Target	LH receptor (luteinizing hormone receptor)
Modality	Small molecule
Therapeutic area	Reproductive/Fertility; Endocrinology
Phase	FDA-approved

Mechanism of action

Pregnyl mimics the natural hormone hCG, which binds to luteinizing hormone (LH) receptors on Leydig cells in males and granulosa cells in females. This stimulates testosterone production in males and progesterone production in females, making it useful for inducing ovulation and treating hypogonadism. The drug is derived from urine of pregnant women or produced via recombinant technology.

Approved indications

Induction of ovulation in anovulatory infertile women
Treatment of hypogonadism in males
Cryptorchidism (undescended testis) in prepubertal boys

Common side effects

Ovarian hyperstimulation syndrome (OHSS)
Headache
Injection site reactions
Abdominal pain/bloating
Nausea

Key clinical trials

Comparison Between hCG and GnRH Agonist for Ovulation Induction in Patients With High Response to IVF Drugs (PHASE4)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Arvekap, Pregnyl CI brief — competitive landscape report
Arvekap, Pregnyl updates RSS · CI watch RSS
Eugonia portfolio CI

Frequently asked questions about Arvekap, Pregnyl

What is Arvekap, Pregnyl?

Arvekap, Pregnyl is a Gonadotropin; human chorionic gonadotropin (hCG) drug developed by Eugonia, indicated for Induction of ovulation in anovulatory infertile women, Treatment of hypogonadism in males, Cryptorchidism (undescended testis) in prepubertal boys.

How does Arvekap, Pregnyl work?

Pregnyl is a human chorionic gonadotropin (hCG) that stimulates the production of sex hormones by acting on gonadal tissue.

What is Arvekap, Pregnyl used for?

Arvekap, Pregnyl is indicated for Induction of ovulation in anovulatory infertile women, Treatment of hypogonadism in males, Cryptorchidism (undescended testis) in prepubertal boys.

Who makes Arvekap, Pregnyl?

Arvekap, Pregnyl is developed and marketed by Eugonia (see full Eugonia pipeline at /company/eugonia).

What drug class is Arvekap, Pregnyl in?

Arvekap, Pregnyl belongs to the Gonadotropin; human chorionic gonadotropin (hCG) class. See all Gonadotropin; human chorionic gonadotropin (hCG) drugs at /class/gonadotropin-human-chorionic-gonadotropin-hcg.

What development phase is Arvekap, Pregnyl in?

Arvekap, Pregnyl is FDA-approved (marketed).

What are the side effects of Arvekap, Pregnyl?

Common side effects of Arvekap, Pregnyl include Ovarian hyperstimulation syndrome (OHSS), Headache, Injection site reactions, Abdominal pain/bloating, Nausea.

What does Arvekap, Pregnyl target?

Arvekap, Pregnyl targets LH receptor (luteinizing hormone receptor) and is a Gonadotropin; human chorionic gonadotropin (hCG).

Drug class: All Gonadotropin; human chorionic gonadotropin (hCG) drugs
Target: All drugs targeting LH receptor (luteinizing hormone receptor)
Manufacturer: Eugonia — full pipeline
Therapeutic area: All drugs in Reproductive/Fertility; Endocrinology
Indication: Drugs for Induction of ovulation in anovulatory infertile women
Indication: Drugs for Treatment of hypogonadism in males
Indication: Drugs for Cryptorchidism (undescended testis) in prepubertal boys

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing