{"id":"arvekap-pregnyl","safety":{"commonSideEffects":[{"rate":null,"effect":"Ovarian hyperstimulation syndrome (OHSS)"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Injection site reactions"},{"rate":null,"effect":"Abdominal pain/bloating"},{"rate":null,"effect":"Nausea"}]},"_chembl":{"chemblId":"CHEMBL1201334","moleculeType":"Protein","molecularWeight":"1311.47"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Pregnyl mimics the natural hormone hCG, which binds to luteinizing hormone (LH) receptors on Leydig cells in males and granulosa cells in females. This stimulates testosterone production in males and progesterone production in females, making it useful for inducing ovulation and treating hypogonadism. The drug is derived from urine of pregnant women or produced via recombinant technology.","oneSentence":"Pregnyl is a human chorionic gonadotropin (hCG) that stimulates the production of sex hormones by acting on gonadal tissue.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:18:44.082Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Induction of ovulation in anovulatory infertile women"},{"name":"Treatment of hypogonadism in males"},{"name":"Cryptorchidism (undescended testis) in prepubertal boys"}]},"trialDetails":[{"nctId":"NCT00415792","phase":"PHASE4","title":"Comparison Between hCG and GnRH Agonist for Ovulation Induction in Patients With High Response to IVF Drugs","status":"UNKNOWN","sponsor":"Eugonia","startDate":"2003-11","conditions":"Infertility","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Arvekap, Pregnyl","genericName":"Arvekap, Pregnyl","companyName":"Eugonia","companyId":"eugonia","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Arvekap and Pregnyl are interventions used to study infertility, specifically in a clinical trial comparing their effectiveness for ovulation induction in patients with high response to IVF drugs. Arvekap is a protein modality, which is also known by other names including Decapeptyl.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}