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Antiplatelet therapy
Antiplatelet therapy is a Antiplatelet agent Small molecule drug developed by Assistance Publique - Hôpitaux de Paris. It is currently FDA-approved for Acute coronary syndrome, Secondary prevention of myocardial infarction, Stroke prevention. Also known as: ticagrelor, aspirin, The brand name of clopidogrel is Plavix., The brand name of cilostazol is Pletaal..
Antiplatelet therapy inhibits platelet aggregation to prevent blood clot formation and reduce thrombotic events.
Antiplatelet therapy inhibits platelet aggregation to prevent blood clot formation and reduce thrombotic events. Used for Acute coronary syndrome, Secondary prevention of myocardial infarction, Stroke prevention.
At a glance
| Generic name | Antiplatelet therapy |
|---|---|
| Also known as | ticagrelor, aspirin, The brand name of clopidogrel is Plavix., The brand name of cilostazol is Pletaal. |
| Sponsor | Assistance Publique - Hôpitaux de Paris |
| Drug class | Antiplatelet agent |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
Antiplatelet agents work by interfering with platelet activation and adhesion through various mechanisms, such as inhibiting cyclooxygenase (aspirin), blocking ADP receptors (clopidogrel, ticagrelor), or inhibiting phosphodiesterase. This prevents platelets from clumping together and forming pathological thrombi that can occlude blood vessels and cause myocardial infarction or stroke.
Approved indications
- Acute coronary syndrome
- Secondary prevention of myocardial infarction
- Stroke prevention
- Peripheral arterial disease
Common side effects
- Bleeding
- Gastrointestinal bleeding
- Dyspepsia
- Intracranial hemorrhage
Key clinical trials
- A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome (PHASE3)
- Medical Treatment With or Without Transcatheter Patent Foramen Ovale Closure (NA)
- Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure (PHASE4)
- OPTIA-AF Trial: Rhythm-Guided Antithrombotic Strategy After AF Ablation (PHASE4)
- A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease (PHASE1, PHASE2)
- Comparing Two PFO Closure Devices in Adults With Previous Stroke or TIA (NA)
- PFO Closure, Oral Anticoagulants or Antiplatelet Therapy After PFO-associated Stroke in Patients Aged 60 to 80 Years (PHASE3)
- Discontinuation of Antithrombotic Treatment Following Patent Foramen Ovale Closure in Young Patients With Cryptogenic Stroke (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Antiplatelet therapy CI brief — competitive landscape report
- Antiplatelet therapy updates RSS · CI watch RSS
- Assistance Publique - Hôpitaux de Paris portfolio CI
Frequently asked questions about Antiplatelet therapy
What is Antiplatelet therapy?
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Is Antiplatelet therapy also known as anything else?
What drug class is Antiplatelet therapy in?
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Related
- Drug class: All Antiplatelet agent drugs
- Manufacturer: Assistance Publique - Hôpitaux de Paris — full pipeline
- Therapeutic area: All drugs in Cardiovascular
- Indication: Drugs for Acute coronary syndrome
- Indication: Drugs for Secondary prevention of myocardial infarction
- Indication: Drugs for Stroke prevention
- Also known as: ticagrelor, aspirin, The brand name of clopidogrel is Plavix., The brand name of cilostazol is Pletaal.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing