Last reviewed · How we verify
Antifungal treatment
Antifungal treatment is a Antifungal agent (class varies by specific drug: azole, polyene, echinocandin, or other) Small molecule drug developed by Hospices Civils de Lyon. It is currently FDA-approved for Fungal infections (specific indication depends on formulation and active ingredient).
Antifungal treatments work by disrupting fungal cell wall or membrane integrity, or inhibiting essential fungal enzymes, thereby killing or stopping the growth of fungal organisms.
Antifungal treatments work by disrupting fungal cell wall or membrane integrity, or inhibiting essential fungal enzymes, thereby killing or stopping the growth of fungal organisms. Used for Fungal infections (specific indication depends on formulation and active ingredient).
At a glance
| Generic name | Antifungal treatment |
|---|---|
| Sponsor | Hospices Civils de Lyon |
| Drug class | Antifungal agent (class varies by specific drug: azole, polyene, echinocandin, or other) |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
Antifungals target structures and processes unique to fungi, such as ergosterol in the fungal cell membrane (disrupted by azoles and polyenes) or fungal cell wall components like beta-glucans (targeted by echinocandins). By interfering with these critical fungal-specific structures, antifungals either cause cell lysis and death or prevent fungal replication, allowing the immune system to clear the infection.
Approved indications
- Fungal infections (specific indication depends on formulation and active ingredient)
Common side effects
- Hepatotoxicity
- Nephrotoxicity
- Infusion-related reactions
- Gastrointestinal disturbances
Key clinical trials
- A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections. (PHASE3)
- A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia (PHASE2)
- Mycological Efficacy and Safety of Ketoconazole 2% Shampoo With a Seven-Day Versus Three-Day Treatment Duration in Pityriasis Versicolor (PHASE4)
- Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma (PHASE1, PHASE2)
- Pharmacokinetics of Caspofungin in Burn Patients (PHASE2, PHASE3)
- Study of the Relationship Between the Pharmacokinetics (PK) and Pharmacodynamics of Venetoclax in Patients With Acute Myeloblastic Leukemia (NA)
- FHD-286 With Low-Dose Weekly Decitabine/Venetoclax in Patients With Acute Myeloid Leukemia (PHASE1)
- A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015) (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Antifungal treatment CI brief — competitive landscape report
- Antifungal treatment updates RSS · CI watch RSS
- Hospices Civils de Lyon portfolio CI
Frequently asked questions about Antifungal treatment
What is Antifungal treatment?
How does Antifungal treatment work?
What is Antifungal treatment used for?
Who makes Antifungal treatment?
What drug class is Antifungal treatment in?
What development phase is Antifungal treatment in?
What are the side effects of Antifungal treatment?
Related
- Drug class: All Antifungal agent (class varies by specific drug: azole, polyene, echinocandin, or other) drugs
- Manufacturer: Hospices Civils de Lyon — full pipeline
- Therapeutic area: All drugs in Infectious Disease
- Indication: Drugs for Fungal infections (specific indication depends on formulation and active ingredient)
- Compare: Antifungal treatment vs similar drugs
- Pricing: Antifungal treatment cost, discount & access