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Analgesic/antipyretic and antihistamine drugs
Analgesic/antipyretic and antihistamine drugs is a Combination analgesic/antipyretic and antihistamine Small molecule drug developed by Genentech, Inc.. It is currently in Phase 3 development for Pain and fever with concurrent allergic symptoms, Cold and flu symptoms with allergy component.
This is a combination drug class that reduces pain and fever through analgesic/antipyretic action while simultaneously blocking histamine receptors to reduce allergic responses.
This is a combination drug class that reduces pain and fever through analgesic/antipyretic action while simultaneously blocking histamine receptors to reduce allergic responses. Used for Pain and fever with concurrent allergic symptoms, Cold and flu symptoms with allergy component.
At a glance
| Generic name | Analgesic/antipyretic and antihistamine drugs |
|---|---|
| Sponsor | Genentech, Inc. |
| Drug class | Combination analgesic/antipyretic and antihistamine |
| Modality | Small molecule |
| Therapeutic area | Pain Management, Allergy/Immunology |
| Phase | Phase 3 |
Mechanism of action
Analgesic/antipyretic agents work by inhibiting prostaglandin synthesis (typically via COX inhibition) to reduce pain and fever, while antihistamines competitively block H1 or H2 histamine receptors to prevent allergic and inflammatory responses. The combination allows simultaneous treatment of pain, fever, and allergy symptoms in a single formulation.
Approved indications
- Pain and fever with concurrent allergic symptoms
- Cold and flu symptoms with allergy component
Common side effects
- Drowsiness
- Gastrointestinal upset
- Headache
- Dizziness
Key clinical trials
- A Study to Evaluate the Efficacy and Safety of CNTO328 Plus Best Supportive Care in Multicentric Castleman's Disease (PHASE2)
- A Study of Rituximab Alternative Dosing Rate in Patients With Previously Untreated Diffuse Large B-cell or Follicular Non-Hodgkin's Lymphoma (RATE) (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Analgesic/antipyretic and antihistamine drugs CI brief — competitive landscape report
- Analgesic/antipyretic and antihistamine drugs updates RSS · CI watch RSS
- Genentech, Inc. portfolio CI
Frequently asked questions about Analgesic/antipyretic and antihistamine drugs
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Related
- Drug class: All Combination analgesic/antipyretic and antihistamine drugs
- Manufacturer: Genentech, Inc. — full pipeline
- Therapeutic area: All drugs in Pain Management, Allergy/Immunology
- Indication: Drugs for Pain and fever with concurrent allergic symptoms
- Indication: Drugs for Cold and flu symptoms with allergy component
- Compare: Analgesic/antipyretic and antihistamine drugs vs similar drugs
- Pricing: Analgesic/antipyretic and antihistamine drugs cost, discount & access