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Amoxicillin hydrate
Amoxicillin hydrate is a beta-lactam antibiotic that inhibits cell wall synthesis in bacteria.
Amoxicillin hydrate is a beta-lactam antibiotic that inhibits cell wall synthesis in bacteria. Used for Uncomplicated urinary tract infections, Acute bacterial otitis media, Pharyngitis and tonsillitis caused by Streptococcus pyogenes.
At a glance
| Generic name | Amoxicillin hydrate |
|---|---|
| Sponsor | Takeda |
| Drug class | Penicillin antibiotic |
| Target | Penicillin-binding proteins (PBPs) |
| Modality | Small molecule |
| Therapeutic area | Infectious diseases |
| Phase | Phase 2 |
Mechanism of action
It does this by binding to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, resulting in the disruption of the cell wall synthesis and ultimately leading to bacterial cell death.
Approved indications
- Uncomplicated urinary tract infections
- Acute bacterial otitis media
- Pharyngitis and tonsillitis caused by Streptococcus pyogenes
Common side effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Allergic reactions
Key clinical trials
- Helicobacter Pylori Infection and Gastric Disease in Bhutan: First Community-Wide, Population-Based Study (NA)
- Drug Use Surveillance of Takecab for "Supplement to Helicobacter Pylori Eradication"
- Study to Assess the Efficacy and Safety of Potassium Clavulanate/Amoxicillin in Children With Acute Bacterial Rhinosinusitis (PHASE3)
- Prognostic Study of Gastric MALT Lymphoma After Eradication of Helicobacter Pylori
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |